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there are 2 possible scenarios 2M,4W and 3M,3W
(2C8 * 4C5) + (3C8 * 3C5) = 140 + 560 = 700 possible combinations
You know that there are invalid cases where the two men are together, so by process of elimination, E (635) is the only valid answer, however I would suspect that the real GMAT would put a few more choices under 700 so you'd have to solve the whole thing.
so 700 total cases, minus the cases where the two jerks are together.
all of comboas that have 2 men that are those two, are invalid, so thats the two of them, paired with every possible set of women, ->5
The 3-men sets that are invalid are the two of them, paired with each of the remaining six men(6), pair each of those with every possible combination of 3 women(10) 6*10 = 60.
so there are 5 invalid combos that have 2 men, and 60 invalid combos that have 3 men.