I don't think getting laid off is a deal breaker. I am in the same situation, I found out at the end of the year and still hadn't done my Darden interview. In the spirit of honestly, I told my interviewer the situation, but I communicated that I understood the business decision my company made (without sounding like I was bitter...) and put an optimistic spin on it (I'm taking classes to prepare, volunteering, etc.). I feel that I came across as sounding business savvy in talking about the details, mature because I wasn't taking it personally, and that I am able to make the most of a challenging situation (IMHO). She actually told me that even though the situation sounded stressful, in the long run, I will look back on it and be thankful for the time I spent preparing for school and that I will probably get more out of the classes I'm taking than working for 6 months. She told me I was setting myself up to have a successful fist semester at school.
Clearly that is just one adcom's perspective, but it didn't seem to bother her that I was laid off. It is a reality of the business world, and just like any experience, adcom are more concerned with how you respond and what you learn than with the situation.
Although I haven't gotten into Darden yet...