You can absolutely change your long-term goals! And maybe even should. An important part of the application process for reapplicants, is, besides showing how much you improved, that you reconsidered what you had done and proposed in last year's application. Of course, you want your goals to make more sense than last year's and not less! So everything is ultimately a case by case decision. But there's no problem with changing your goals, as long as you explain your logic.
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