The answer is A. If blood cannot absorb more nicotine than what is found in the lowest nicotine cigarettes, there is no reason higher nicotine cigarettes should produce higher levels of nicotine in blood samples.
B is tempting, but is not correct; the stem already tells us the study *only* looked at people smoking exactly one pack per day. So the study controlled for the number of cigarettes smoked. C tells us that low-nicotine cigarettes still deliver nicotine, which does nothing to explain why there is no difference between low and high nicotine smokes. Tar is irrelevant, so D is wrong. The wording of E is completely unclear, so it's hard to even evaluate. If it were the case that nicotine levels dropped very quickly moments after smoking, then E would be a very good answer here too, since that would mean no one has high nicotine levels at the end of the day besides people who just smoked a cigarette; the nicotine level of cigarettes would be irrelevant. I don't think that's what the question writer meant by E, however, even though it could be interpreted that way.
Because the writing of the question is quite bad, it is a bit tricky to answer; in C the word 'it' should clearly refer back to 'nicotine' for example, and the wording of E is so imprecise that it's impossible to know exactly what it means. Where is the question from?
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