Yeah OA is E but don't you think while should be used only when you are simultaneously doing two works
Hi Angel, I think your note about "while" applies to this context. You are correct; "while" is used when you are doing two things simultaneously. But almost any kind of noun can do two things at once; my kitchen can do two things at once; the GMAT can do two things at once. ("The GMAT stresses me out while honing my guessing skills.")
Here, the subject of the clause is the "disease." The "disease" can do two things simultaneously, just like you can do two pieces of work at once.
Think of the disease as an active entity. It can do two activities at once. The two activities are "afflicting" and "sparing." Thus the disease "afflicts" some people while
Just my $0.02. Any other thoughts?