In an effort to develop a treatment regimen that would effectively reduce the number and severity of outbreaks in patients who suffer from adult acne, the pharmaceutical company Skinworth directed dermatologists participating in its research study to increase the dosage of the medication that had been proven to reduce bacteria on the skin and diminish blemishes and redness. Accordingly, the patients taking part in the study followed the doctors’ instructions and regularly used the higher doses of the medication. Nonetheless, the patients reported that the condition of their skin had worsened somewhat.Which of the following, if true, most helps to explain why acting on the dermatologists’ instructions failed to achieve the research study’s goal?
A] The change in dosage increased the amount of the drug required, making the treatment significantly more expensive.
B] The amount of medication used does not significantly affect the ease with which patients can follow their treatment regimens.
C] Most of the patients participating in Skinworth’s study have severe problems with acne and are especially vulnerable to sudden flare-ups.
D] When too much of the drug is used, it irritates the skin, causing bumps and splotching.
E] Some of the patients participating resigned from Skinworth’s study because they were unsatisfied with the results of the treatment.