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In prenatal testing for spina bifida, a life threatening

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In prenatal testing for spina bifida, a life threatening [#permalink] New post 25 May 2009, 10:07
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In prenatal testing for spina bifida, a life threatening disease, a false positive result indicates that an fetus has spina bifida when, in fact, it does not; a false negative result indicates that a fetus does not have spina bifida when, in fact, it does. To detect spina bifida most accurately, physicians should use the laboratory test that has the lowest proportion of false positive results.

Which of the following, if true, gives the most support to the recommendation above?

A. All laboratory tests to detect spina bifida have the same proportion of false negative results.
B. The laboratory test that has the lowest proportions of false positive results causes the same minor side effects as do the other laboratory tests used to detect spina bifida.
C. In treating spina bifida patients, it is essential to begin treatment as early as possible, since even a week of delay can result in loss of life.
D. The proportion of inconclusive test results is equal for all laboratory tests used to detect spina bifida.
E. The accepted treatment for spina bifida does not have damaging side effects.
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Re: prenatal testing for spina bifida [#permalink] New post 25 May 2009, 10:45
mbaMission wrote:
In prenatal testing for spina bifida, a life threatening disease, a false positive result indicates that an fetus has spina bifida when, in fact, it does not; a false negative result indicates that a fetus does not have spina bifida when, in fact, it does. To detect spina bifida most accurately, physicians should use the laboratory test that has the lowest proportion of false positive results.

Which of the following, if true, gives the most support to the recommendation above?

A. All laboratory tests to detect spina bifida have the same proportion of false negative results.
B. The laboratory test that has the lowest proportions of false positive results causes the same minor side effects as do the other laboratory tests used to detect spina bifida.
C. In treating spina bifida patients, it is essential to begin treatment as early as possible, since even a week of delay can result in loss of life.
D. The proportion of inconclusive test results is equal for all laboratory tests used to detect spina bifida.
E. The accepted treatment for spina bifida does not have damaging side effects.


I think this (or something like it) has been posted before. I think the answer should be (A).

B - This says there is not much difference, not a strong answer.
C - This is more of a weaken than anything else.
D - This suggests again, that there is no difference between the different test equipment, not a strong answer.
E - Kind of irrelevant...

(A) This suggests all equipment used for detection have the same false negative rates, so the most accurate test is the one with the lowest false positive. This corresponds with the original info.
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Re: prenatal testing for spina bifida [#permalink] New post 28 May 2009, 01:49
I really had to think about this.

I was going under the assumption that a certain % of overall results would always be either FN or FP (false negative/false positive). But if FN is the same, and you want the most accurate test, you obviouslywant to minimize FP... otherwise it could be the case that the test with the lower FP rate has a higher FN rate (which could neutralize or cancel out the lower FP benefits).

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Re: prenatal testing for spina bifida [#permalink] New post 28 May 2009, 21:41
yup A
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Re: prenatal testing for spina bifida [#permalink] New post 29 May 2009, 00:35
A for me.
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Re: prenatal testing for spina bifida [#permalink] New post 13 Mar 2010, 12:54
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Re: prenatal testing for spina bifida   [#permalink] 13 Mar 2010, 12:54
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