In response to viral infection, the immune systems of mice : GMAT Critical Reasoning (CR) - Page 2
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# In response to viral infection, the immune systems of mice

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Manager
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20 Jun 2006, 08:53
not clear about the last line " caused by antibodies to herpes virus"

Scientists hypothosize that anti-bodies cause this disease in which they attach to the the protein on the surface of this virus

Also, the protein is similar to that on the eye ... so the antibodies if produced can attach itself to the protein on the eye and cause the disease too.
Option E states this
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20 Jun 2006, 08:58
Clearly D

E is out because there are may be other factors that cause the deasease, not necessarily antibodies. So it doesn't prove or refute anything.
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20 Jun 2006, 09:02
option D states that there are no antibodies but the mice survive the infection ???

this makes the antibodies redundant ... mice cannot survive the infection without antibodies
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20 Jun 2006, 09:13
foolz_rulz wrote:
option D states that there are no antibodies but the mice survive the infection ???

this makes the antibodies redundant ... mice cannot survive the infection without antibodies

See my additions to the previous post.

As to your arguments, there are plenty of deseases that humans survive for years without developing antibodies. With reduced immunity, one doesn't develop enough antibodies even to the most common deseases. However, taking antibiotics, one can survive for years.

Now to the question, we are told nothing about how those mice actually survived the desease. May be they were given antibiotics or other drugs to suppress the desease.
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20 Jun 2006, 09:43
I'll go with D.
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20 Jun 2006, 09:49
Will go with D.

The hypothesis is that the keratitis are formed by the antibodies for the herpes virus.
To support this hypothesis we have to show that mice that dont produce the antibodies done contract heratitis.
THis is stated in D
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20 Jun 2006, 09:59
D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
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20 Jun 2006, 13:20
D.
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21 Jun 2006, 04:43
OA is D
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21 Jun 2006, 07:26
Phew! (D) supports the scientists claim.

Tip, on "which of the following" CRs, always start with E and work up.

2:16
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In response to viral infection, the immune systems of mice [#permalink]

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02 Sep 2006, 21:03
In response to viral infection, the immune systems of mice typically produce antibodies that destroy the virus by binding to proteins on its surface. Mice infected with a herpesvirus generally develop keratitis, a degenerative disease affecting part of the eye. Since proteins on the surface of cells in this part of the eye closely resemble those on the herpesvirus surface, scientists hypothesize that these cases of keratitis are caused by antibodies to herpesvirus.

Which of the following, if true, gives the greatest additional support to the scientistsâ€™ hypothesis?

A. Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.
B. There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.
C. Mice that are infected with a herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.
D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
E. Mice that have never been infected with a herpesvirus can sometimes develop keratitis.
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02 Sep 2006, 23:24
D?
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02 Sep 2006, 23:26
D

If mice can not produce antibodies in respose to herpesvirus then they can't develop keratitis. Hence the only cause of keratitis is the antibodies developed in response to herpesvirus.
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Re: CR-Mice infected with a herpesvirus [#permalink]

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03 Sep 2006, 02:28
jerrywu wrote:
Scientists hypothesize that these cases of keratitis are caused by antibodies to herpesvirus.

A. Other types of virus have surface proteins that closely resemble proteins found in various organs of mice.
B. There are mice that are unable to form antibodies in response to herpes infections, and these mice contract herpes at roughly the same rate as other mice.
C. Mice that are infected with a herpesvirus but do not develop keratitis produce as many antibodies as infected mice that do develop keratitis.
D. There are mice that are unable to form antibodies in response to herpes infections, and these mice survive these infections without ever developing keratitis.
E. Mice that have never been infected with a herpesvirus can sometimes develop keratitis.

D for me. Hypothesis is about keratitis and not the herpes infection itself. So, in D, mice without antibodies do not develop keratitis -> clearly supports hypothesis.
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D for me as well [#permalink]

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03 Sep 2006, 14:14
D for me as well
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04 Sep 2006, 00:05
D is the right one here
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04 Sep 2006, 01:50
One more vote for D
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04 Sep 2006, 04:00
Yup D...
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Re: CR - Viral infection [#permalink]

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29 Jul 2010, 08:26
Im afraid to say that answer is B.
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Re: CR - Viral infection [#permalink]

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29 Jul 2010, 09:59
noboru wrote:
Im afraid to say that answer is B.

I get D at the following link
cr-a-must-to-try-30855.html?hilit=In%20response%20to%20viral%20infection,#p209908
Re: CR - Viral infection   [#permalink] 29 Jul 2010, 09:59

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