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Macrophages are cells that play a role in the response of [#permalink]
 06 Nov 2005, 12:45
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Macrophages are cells that play a role in the response of the immune system of mice and other mammals to invasive organisms such as bacteria. Unlike other mice, mice that are genetically incapable of making these particular cells do not show elevated levels of nitrates when infected with bacteria.
The statements above, if true, provide the most support for which of the following conclusions?
A. Mice that are unable either to make macrophages or to make them in sufficient numbers will protect themselves from bacterial infections in some other way.
B. Mice that show elevated levels of nitrates can easily fight off most types of bacterial infections.
C. In mice, macrophages play a role in the production of nitrates or inhibit a process by which nitrates are broken down or otherwise eliminated.
D. When a healthy mouse becomes infected with an invasive organism, the number of macrophages in the mouse’s body decreases.
E. Injections of nitrates into mice that lack macrophages will not enhance the ability of these animals’ immune systems to fight off infection.
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Re: CR # Macrophages [#permalink]
06 Nov 2005, 12:55
I strongly support C.
In Mice: bacteria lead to elevated levels of nitrates. bacteria activate macrophages. To close this circle a connection between macrophage and nitrates must exist which is answer C
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Re: CR # Macrophages [#permalink]
06 Nov 2005, 22:57
sandalphon wrote: I strongly support C.
In Mice: bacteria lead to elevated levels of nitrates. bacteria activate macrophages. To close this circle a connection between macrophage and nitrates must exist which is answer C
TRUE, TRUE !
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I vote for C
A,B,D, E - Infer too much and bring in data which is out of scope.
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One more vote for C
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C too 
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Good job guys. C is the OA.
I was stuck between B and C. I understand that C is correct, but how do u eliminate B.
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nakib77 wrote: Good job guys. C is the OA.
I was stuck between B and C. I understand that C is correct, but how do u eliminate B.
The author says that macrophages are good against invasive organisms such as bacteria, and (B) says that macrophages are good against MOST TYPES OF BACTERIAL INFECTIONS.
We do not know if it is good against MOST bacteria.
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nakib77 wrote: Good job guys. C is the OA.
I was stuck between B and C. I understand that C is correct, but how do u eliminate B.
I think we must differentiate here between "show a response" and "easily fight off". These two things are not similar.
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I eliminated B because it was too extreme :
B. Mice that show elevated levels of nitrates can easily fight off most types of bacterial infections.
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All except C are irrelevant or out of scope. therefore C must be.
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