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# Colfax Beta-80 is a rare genetic defect found primarily in

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Magoosh GMAT Instructor
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Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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05 Jun 2013, 09:53
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53% (02:07) correct 47% (02:01) wrong based on 910 sessions

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Colfax Beta-80 is a rare genetic defect found primarily in people of Scandinavian descent. Over 97% of known carriers of this defect have are citizens of, or are direct descendants of immigrants from, Denmark, Norway, and Sweden. People who carry the Colfax Beta-80 defect are at substantially higher risk for contracting Lupus and related autoimmune diseases.

Assuming the statements above are true, which of the following can be inferred from them?
(A) People from Denmark are at a higher risk for Lupus than people of other, non-Scandinavian countries.
(B) Genetic engineering that eradicated this genetic defect would constitute a de facto cure for Lupus.
(C) Find a cure for Lupus would eliminate most of the health threats associated with the Colfax Beta-80 defect.
(D) A person not of Scandinavian descent born with the Colfax Beta-80 defect is more likely to contract Lupus than is a Scandinavian who is born without this defect.
(E) The majority of people who contract Lupus are either Scandinavian or of Scandinavian descent
.

Some CR questions deal with the tricky issues of populations & proportions & percents. For a discussion of this genre, with common fallacies, as well as a full explanation of this question, see:
http://magoosh.com/gmat/2013/gmat-criti ... pulations/

Mike

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Re: Colfax Beta-80 is a rare genetic defect found primarily  [#permalink]

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05 Jun 2013, 10:59
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Colfax Beta-80 is a rare genetic defect found primarily in people of Scandinavian descent. Over 97% of known carriers of this defect have are citizens of, or are direct descendants of immigrants from, Denmark, Norway, and Sweden. People who carry the Colfax Beta-80 defect are at substantially higher risk for contracting Lupus and related autoimmune diseases.

Assuming the statements above are true, which of the following can be inferred from them?
(A) People from Denmark are at a higher risk for Lupus than people of other, non-Scandinavian countries.
(B) Genetic engineering that eradicated this genetic defect would constitute a de facto cure for Lupus.
(C) Find a cure for Lupus would eliminate most of the health threats associated with the Colfax Beta-80 defect.
(D) A person not of Scandinavian descent born with the Colfax Beta-80 defect is more likely to contract Lupus than is a Scandinavian who is born without this defect.
(E) The majority of people who contract Lupus are either Scandinavian or of Scandinavian descent[/color].

Some CR questions deal with the tricky issues of populations & proportions & percents. For a discussion of this genre, with common fallacies, as well as a full explanation of this question, see:
http://magoosh.com/gmat/2013/gmat-criti ... pulations/

Mike

A) we have substantially higher risk VS higher risk and only this changes completely the scenario

B) What the genetic engeneering does is not our concern

C) wrong because is excactly the contrary

D) CORRECT

E) We talk about risk not who contract the Lupus

Good one
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Re: Colfax Beta-80 is a rare genetic defect found primarily  [#permalink]

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05 Jun 2013, 13:33
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Detailed Explanation please, got confused big time between D and E and ultimately went for E
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Re: Colfax Beta-80 is a rare genetic defect found primarily  [#permalink]

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05 Jun 2013, 14:17
IvyLeague56 wrote:
Detailed Explanation please, got confused big time between D and E and ultimately went for E

http://magoosh.com/gmat/2013/gmat-criti ... pulations/
Mike
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Colfax Beta-80 is a rare genetic defect found primarily in people of S  [#permalink]

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12 Oct 2015, 11:50
Colfax Beta-80 is a rare genetic defect found primarily in people of Scandinavian descent. Over 97% of known carriers of this defect are citizens of, or are direct descendants of immigrants from, Denmark, Norway, and Sweden. People who carry the Colfax Beta-80 defect are at substantially higher risk for contracting Lupus and related autoimmune diseases.
Assuming the statements above are true, which of the following can be inferred from them?

(A) People from Denmark are at a higher risk for Lupus than people of other, non-Scandinavian countries.

(B) Genetic engineering that eradicated this genetic defect would constitute a de facto cure for Lupus.

(C) Find a cure for Lupus would eliminate most of the health threats associated with the Colfax Beta-80 defect.

(D) A person not of Scandinavian descent born with the Colfax Beta-80 defect is more likely to contract Lupus than is a Scandinavian who is born without this defect.

(E) The majority of people who contract Lupus are either Scandinavian or of Scandinavian descent.
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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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13 Oct 2015, 14:59
tuanquang269 wrote:
Colfax Beta-80 is a rare genetic defect found primarily in people of Scandinavian descent. Over 97% of known carriers of this defect are citizens of, or are direct descendants of immigrants from, Denmark, Norway, and Sweden. People who carry the Colfax Beta-80 defect are at substantially higher risk for contracting Lupus and related autoimmune diseases.
Assuming the statements above are true, which of the following can be inferred from them?

(A) People from Denmark are at a higher risk for Lupus than people of other, non-Scandinavian countries.

(B) Genetic engineering that eradicated this genetic defect would constitute a de facto cure for Lupus.

(C) Find a cure for Lupus would eliminate most of the health threats associated with the Colfax Beta-80 defect.

(D) A person not of Scandinavian descent born with the Colfax Beta-80 defect is more likely to contract Lupus than is a Scandinavian who is born without this defect.

(E) The majority of people who contract Lupus are either Scandinavian or of Scandinavian descent.

Topics merged. tuanquang269, please search for a question before beginning a new thread.
Thank you,
Mike
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Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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20 Oct 2015, 11:04
• Colfax Beta-80 is a rare genetic defect found primarily in people of Scandinavian descent.
• Over 97% of known carriers of this defect have are citizens of, or are direct descendants of immigrants from, Denmark, Norway, and Sweden.
• People who carry the Colfax Beta-80 defect are at substantially higher risk for contracting Lupus and related autoimmune diseases

Assuming the statements above are true, which of the following can be inferred from them?

(A) People from Denmark are at a higher risk for Lupus than people of other, non-Scandinavian countries.
(B) Genetic engineering that eradicated this genetic defect would constitute a de facto cure for Lupus...............nothing of this sort is mentioned in the argument. There is no mention of defect eradication.
(C) Find a cure for Lupus would eliminate most of the health threats associated with the Colfax Beta-80 defect.........cure for Lupus is neither mentioned nor discussed
(D) A person not of Scandinavian descent born with the Colfax Beta-80 defect is more likely to contract Lupus than is a Scandinavian who is born without this defect.
(E) The majority of people who contract Lupus are either Scandinavian or of Scandinavian descent.............we are not sure of this since we only know majority of people with defect are from Scandinavian descent. And these may contain high risk of contracting Lupus but need not contract Lupus compulsorily.

chose A out of A and D.

Important lesson wrote:
Most folks with this genetic defect are Scandinavian, but that doesn’t imply that most Scandinavian people have this defect. People with the defect are at higher risk for Lupus, but that doesn’t mean large sections of the Scandinavian population are at risk for Lupus.
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Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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09 May 2018, 07:30
1

Official Explanation

The prompt tells us that Colfax Beta-80 is a genetic defect. Most of the folks who have this defect are Scandinavian, but we don't know what percent of Scandinavians have this defect. It may be a substantial portion, but that's unlikely because the defect is "rare." Much more likely: there only be a couple hundred people in the whole world who have this defect, and 97% of this couple hundred are from Scandinavia ---- a large percentage among those with the defect, but not a large percentage among the Scandinavian population as a whole. A couple answer choices conflate these two percentages.

Anyone with this defect is at higher risk for Lupus and other autoimmune diseases.

(D) is the credited answer. This more or less restates the information of the last sentence. Anyone with this defect (Scandinavian or not) has a substantially higher risk of Lupus compared to anyone without the defect (Scandinavian or not).

(A) & (E) play on the misunderstanding about what the 97% implies. Most folks with this genetic defect are Scandinavian, but that doesn’t imply that most Scandinavian people have this defect. People with the defect are at higher risk for Lupus, but that doesn't mean large sections of the Scandinavian population are at risk for Lupus.

(B) is wrong because, while we are told this genetic defect causes susceptibility to Lupus, we don't know what other factors might cause or contribute to Lupus. Just because we eliminate this one factor does not mean we would eliminate everything in the world that could possibly contribute to the onset of Lupus.

(C) is wrong because, while we are told this genetic defect causes Lupus, we are also told it causes other autoimmune diseases. Even if we had a cure for Lupus, these other autoimmune diseases would still poses health threats to carriers of the defect.
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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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27 Oct 2018, 19:16
mikemcgarry wrote:
Colfax Beta-80 is a rare genetic defect found primarily in people of Scandinavian descent. Over 97% of known carriers of this defect have are citizens of, or are direct descendants of immigrants from, Denmark, Norway, and Sweden. People who carry the Colfax Beta-80 defect are at substantially higher risk for contracting Lupus and related autoimmune diseases.

Assuming the statements above are true, which of the following can be inferred from them?
(A) People from Denmark are at a higher risk for Lupus than people of other, non-Scandinavian countries.
(B) Genetic engineering that eradicated this genetic defect would constitute a de facto cure for Lupus.
(C) Find a cure for Lupus would eliminate most of the health threats associated with the Colfax Beta-80 defect.
(D) A person not of Scandinavian descent born with the Colfax Beta-80 defect is more likely to contract Lupus than is a Scandinavian who is born without this defect.
(E) The majority of people who contract Lupus are either Scandinavian or of Scandinavian descent
.

Some CR questions deal with the tricky issues of populations & proportions & percents. For a discussion of this genre, with common fallacies, as well as a full explanation of this question, see:
http://magoosh.com/gmat/2013/gmat-criti ... pulations/

Mike

GMAT likes to play with quantity and percentage, makes different traps.
I will add a little about A and E (especially A) (B, C are obviously out).
(A) People from Denmark are at a higher risk for Lupus than people of other, non-Scandinavian countries.
So, Beta-80 is rare ---> small amount of such people. It is bad for lupus. Yes, Sure.
But maybe there is another defect (XXX) and (it is not that rare in another country) there a lot of such people in Germany for example, and this XXX is bad for lupus too.
So people from Germany are at higher risk for Lupus than people of Denmark ---> A is wrong.
(Same logic applies to E)

So D
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Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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28 Nov 2018, 18:13
aragonn wrote:

Official Explanation

The prompt tells us that Colfax Beta-80 is a genetic defect. Most of the folks who have this defect are Scandinavian, but we don't know what percent of Scandinavians have this defect. It may be a substantial portion, but that's unlikely because the defect is "rare." Much more likely: there only be a couple hundred people in the whole world who have this defect, and 97% of this couple hundred are from Scandinavia ---- a large percentage among those with the defect, but not a large percentage among the Scandinavian population as a whole. A couple answer choices conflate these two percentages.

Anyone with this defect is at higher risk for Lupus and other autoimmune diseases.

(D) is the credited answer. This more or less restates the information of the last sentence. Anyone with this defect (Scandinavian or not) has a substantially higher risk of Lupus compared to anyone without the defect (Scandinavian or not).

(A) & (E) play on the misunderstanding about what the 97% implies. Most folks with this genetic defect are Scandinavian, but that doesn’t imply that most Scandinavian people have this defect. People with the defect are at higher risk for Lupus, but that doesn't mean large sections of the Scandinavian population are at risk for Lupus.

(B) is wrong because, while we are told this genetic defect causes susceptibility to Lupus, we don't know what other factors might cause or contribute to Lupus. Just because we eliminate this one factor does not mean we would eliminate everything in the world that could possibly contribute to the onset of Lupus.

(C) is wrong because, while we are told this genetic defect causes Lupus, we are also told it causes other autoimmune diseases. Even if we had a cure for Lupus, these other autoimmune diseases would still poses health threats to carriers of the defect.

Hi aragonn,

I feel the explanation given for elimination of A & E can be improved. I feel the better version can be that Lupus can be caused by several other viruses/pathogens etc.(other than from Beta-80).
If total no. of lupus-affected-people in the world are 1 Million & there are only 100 who have lupus because of Beta-40 then A & E can be eliminated.

Elimination of A - It may happen that out of 1 million, 200,000 are from one specific(say country X; I don't want to name any country here) non-scandivian country.

Elimination of E - Covered above. A non-scandivian country can have a majority of those 1 million people.

Let me know if there is any disagreement on this.
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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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28 Nov 2018, 18:46
AKY13 - With all due respect mate, I think you are missing some info in your argument construction. Take a look once. The basis of elimination of both A and E is completely in wrong direction in your explanation. I say you try one more time. Read OE too, if you have too. I encourage you to Write a full POE. I will for sure help you in finding these gaps.
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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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29 Nov 2018, 17:02
aragonn wrote:
AKY13 - With all due respect mate, I think you are missing some info in your argument construction. Take a look once. The basis of elimination of both A and E is completely in wrong direction in your explanation. I say you try one more time. Read OE too, if you have too. I encourage you to Write a full POE. I will for sure help you in finding these gaps.

Thanks Aragonn,
You made me relook the reasoning; it seems that I am biased to be able to find out the gaps in reasoning.
Pls help me find specific gaps in my reasoning.
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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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29 Nov 2018, 20:04
Please find my response in line.

I feel the explanation given for elimination of A & E can be improved. I feel the better version can be that Lupus can be caused by several other viruses/pathogens etc.(other than from Beta-80).
If total no. of lupus-affected-people in the world are 1 Million & there are only 100 who have lupus because of Beta-40 then A & E can be eliminated.

Elimination of A - It may happen that out of 1 million, 200,000 are from one specific(say country X; I don't want to name any country here) non-scandivian country. ------ Do you know this information. This is a inference question. Scope is your best friend. be sure about what you know and what you dont. such as we cant pick this choice cause we don't have sufficient information. now lets look at your point. Are you sure this may happen with the ration you mentioned ( 1 million, 200,000). Do you have any basis for this ?

Elimination of E - Covered above. A non-scandivian country can have a majority of those 1 million people. ---- same explanation applies to it too.

My friend inference is most easy part in CR. This is one thing in which you dont need to do POE. If you sure about a choice that it is true, go ahead then. Though I will still advice to do POE. And for that look for the scope. Look for information given to you and do not go beyond that.
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Thanks!
Do give some kudos.

Simple strategy:
“Once you’ve eliminated the impossible, whatever remains, however improbable, must be the truth.”

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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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30 Nov 2018, 16:25
aragonn wrote:
Please find my response in line.

I feel the explanation given for elimination of A & E can be improved. I feel the better version can be that Lupus can be caused by several other viruses/pathogens etc.(other than from Beta-80).
If total no. of lupus-affected-people in the world are 1 Million & there are only 100 who have lupus because of Beta-40 then A & E can be eliminated.

Elimination of A - It may happen that out of 1 million, 200,000 are from one specific(say country X; I don't want to name any country here) non-scandivian country. ------ Do you know this information. This is a inference question. Scope is your best friend. be sure about what you know and what you dont. such as we cant pick this choice cause we don't have sufficient information. now lets look at your point. Are you sure this may happen with the ration you mentioned ( 1 million, 200,000). Do you have any basis for this ?

Elimination of E - Covered above. A non-scandivian country can have a majority of those 1 million people. ---- same explanation applies to it too.

My friend inference is most easy part in CR. This is one thing in which you dont need to do POE. If you sure about a choice that it is true, go ahead then. Though I will still advice to do POE. And for that look for the scope. Look for information given to you and do not go beyond that.

Hi Aragonn
Thanks for the help.

I have brought in the figures to eliminate A & E not to choose them. I have tried to weaken A & E by bringing in some data(which if valid would weaken). This additional data can't be disputed by the argument.

In this case, I assumed that Lupus is caused by several other factors as well. It is nowhere mentioned in the argument that the Lupus is only caused by Beta.
X causes Y
A, B, C, D also causes Y
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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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30 Nov 2018, 20:28
On what grounds you assumed this. ----- In this case, I assumed that Lupus is caused by several other factors as well. It is nowhere mentioned in the argument that the Lupus is only caused by Beta.

My friend, in inference questions, if you assume even small things, it can cause a lot worse. I bet if I add another choice with this assumption you will mark it an answer. All I am saying is, this time by luck you did not fall in trap but this will not happen all the time. there is a gap in your strategy fill this gap. "strictly No assumptions" in inference questions. Even it is not an inference question this assumption is not True.
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Thanks!
Do give some kudos.

Simple strategy:
“Once you’ve eliminated the impossible, whatever remains, however improbable, must be the truth.”

GMAT Ninja YouTube! Series 1| GMAT Ninja YouTube! Series 2 | How to Improve GMAT Quant from Q49 to a Perfect Q51 | Time management

My Notes:
Reading comprehension | Critical Reasoning | Absolute Phrases | Subjunctive Mood
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Re: Colfax Beta-80 is a rare genetic defect found primarily in  [#permalink]

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01 Dec 2018, 18:47
aragonn wrote:
On what grounds you assumed this. ----- In this case, I assumed that Lupus is caused by several other factors as well. It is nowhere mentioned in the argument that the Lupus is only caused by Beta.

My friend, in inference questions, if you assume even small things, it can cause a lot worse. I bet if I add another choice with this assumption you will mark it an answer. All I am saying is, this time by luck you did not fall in trap but this will not happen all the time. there is a gap in your strategy fill this gap. "strictly No assumptions" in inference questions. Even it is not an inference question this assumption is not True.

Thanks Aragonn for trying to help me.
I feel the inference must be steadfast for the argument & should not get deterred by some additional information(unless it doesn't dispute premise).
Re: Colfax Beta-80 is a rare genetic defect found primarily in   [#permalink] 01 Dec 2018, 18:47
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