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Healthy lungs produce a natural antibiotic that protects them from inf

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Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 23 Feb 2009, 16:41
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Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibroses, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic. Since the fluid on airway surfaces in the lungs of people with cystic fibrosis bas an abnormally high salt concentration, scientists hypothesize that in high salt environments the antibiotic becomes ineffective at killing harmful bacteria.

Which of the following, if it were obtained as an experimental result, would most decisively undermine the scientists’ hypothesis?

(A) Healthy lungs in which the salt concentration of the airway-surface fluid has been substantially increased are able to reestablish their normal salt concentration within a relatively short period of time.

(B) The antibiotic produced by the lungs is effective at killing harmful bacteria even when salt concentrations are below levels typical of healthy lungs.

(C) The salt concentration of the airway-surface fluid in the lungs of people who suffer from cystic fibrosis tends to return to its former high levels after having been reduced to levels typical of healthy lungs.

(D) The lungs of people who suffer from cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced to levels typical of healthy lungs.

(E) The salt concentration in the airway-surface fluid of people whose lungs produce lower-than-average amounts of the antibiotic is generally much lower than that typical of healthy lungs.
[Reveal] Spoiler: OA

Last edited by hazelnut on 21 Oct 2017, 23:03, edited 1 time in total.
Edited the question.

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Re: Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 23 Feb 2009, 17:26
D is the best answer

Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibroses, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic. Since the fluid on airway surfaces in the lungs of people with cystic fibrosis bas an abnormally high salt concentration, scientists hypothesize that in high salt environments the antibiotic becomes ineffective at killing harmful bacteria.

Which of the following, if it were obtained as an experimental result, would most decisively undermine the scientists’ hypothesis?

A. Healthy lungs in which the salt concentration of the airway-surface fluid has been substantially increased are able to reestablish their normal salt concentration within a relatively short period of time. - Out of Scope
B. The antibiotic produced by the lungs is effective at killing harmful bacteria even when salt concentrations are below levels typical of healthy lungs.
C. The salt concentration of the airway-surface fluid in the lungs of people who suffer from cystic fibrosis tends to return to its former high levels after having been reduced to levels typical of healthy lungs. - WHO CARES??
D. The lungs of people who suffer from cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced to levels typical of healthy lungs. - BEST ANSWER
E. The salt concentration in the airway-surface fluid of people whose lungs produce lower-than-average amounts of the antibiotic is generally much lower than that typical of healthy lungs. - Irrelevant

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New post 23 Feb 2009, 17:54
Could you please explain the answer?
axl_oz wrote:
D is the best answer

Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibroses, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic. Since the fluid on airway surfaces in the lungs of people with cystic fibrosis bas an abnormally high salt concentration, scientists hypothesize that in high salt environments the antibiotic becomes ineffective at killing harmful bacteria.

Which of the following, if it were obtained as an experimental result, would most decisively undermine the scientists’ hypothesis?

A. Healthy lungs in which the salt concentration of the airway-surface fluid has been substantially increased are able to reestablish their normal salt concentration within a relatively short period of time. - Out of Scope
B. The antibiotic produced by the lungs is effective at killing harmful bacteria even when salt concentrations are below levels typical of healthy lungs.
C. The salt concentration of the airway-surface fluid in the lungs of people who suffer from cystic fibrosis tends to return to its former high levels after having been reduced to levels typical of healthy lungs. - WHO CARES??
D. The lungs of people who suffer from cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced to levels typical of healthy lungs. - BEST ANSWER
E. The salt concentration in the airway-surface fluid of people whose lungs produce lower-than-average amounts of the antibiotic is generally much lower than that typical of healthy lungs. - Irrelevant

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Re: Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 24 Feb 2009, 14:23
Wow, what a confusing one. I go with D as well.

D. The lungs of people who suffer from cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced to levels typical of healthy lungs. - BEST ANSWER

This eliminates the possibility that salt is the cause for the antibiotic to be ineffective. It provides an alternate cause, telling us that it's actually the lungs' inability to fight bacteria that is the issue at hand.

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Re: Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 24 Feb 2009, 20:47
Yeah, D provides alternative explanation for the ineffectiveness of the antibiotic undermining the conclusion

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Re: Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 24 Feb 2009, 22:53
we have to show that
ppl with cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced


IMO D

reply2spg wrote:
Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibroses, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic. Since the fluid on airway surfaces in the lungs of people with cystic fibrosis bas an abnormally high salt concentration, scientists hypothesize that in high salt environments the antibiotic becomes ineffective at killing harmful bacteria.

Which of the following, if it were obtained as an experimental result, would most decisively undermine the scientists’ hypothesis?

A. Healthy lungs in which the salt concentration of the airway-surface fluid has been substantially increased are able to reestablish their normal salt concentration within a relatively short period of time.
B. The antibiotic produced by the lungs is effective at killing harmful bacteria even when salt concentrations are below levels typical of healthy lungs.
C. The salt concentration of the airway-surface fluid in the lungs of people who suffer from cystic fibrosis tends to return to its former high levels after having been reduced to levels typical of healthy lungs.
D. The lungs of people who suffer from cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced to levels typical of healthy lungs.
E. The salt concentration in the airway-surface fluid of people whose lungs produce lower-than-average amounts of the antibiotic is generally much lower than that typical of healthy lungs.

Don't have OA for this.

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Re: Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 24 Feb 2009, 22:54
Another D

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Re: Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 25 Feb 2009, 02:37
Scientists have hypothesized that salt is the function inhibitor of the antibiotic.
Option D clearly annuls the hypothesis.

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New post 27 Feb 2009, 02:57
Though a bit late.....
IMO D...

Option D provides the best alternative explanation that its not the salt level, but the lungs itselfs which are causing the problem

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New post 27 Feb 2009, 07:04
OA PLEASE.

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New post 12 Aug 2015, 01:28
OA is D.

However, can someone help me on what's wrong with B?

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Re: Healthy lungs produce a natural antibiotic that protects them from inf [#permalink]

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New post 19 Nov 2017, 03:27
reply2spg wrote:
Healthy lungs produce a natural antibiotic that protects them from infection by routinely killing harmful bacteria on airway surfaces. People with cystic fibroses, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic. Since the fluid on airway surfaces in the lungs of people with cystic fibrosis bas an abnormally high salt concentration, scientists hypothesize that in high salt environments the antibiotic becomes ineffective at killing harmful bacteria.

Which of the following, if it were obtained as an experimental result, would most decisively undermine the scientists’ hypothesis?

(A) Healthy lungs in which the salt concentration of the airway-surface fluid has been substantially increased are able to reestablish their normal salt concentration within a relatively short period of time.

(B) The antibiotic produced by the lungs is effective at killing harmful bacteria even when salt concentrations are below levels typical of healthy lungs.

(C) The salt concentration of the airway-surface fluid in the lungs of people who suffer from cystic fibrosis tends to return to its former high levels after having been reduced to levels typical of healthy lungs.

(D) The lungs of people who suffer from cystic fibrosis are unable to fight off harmful bacteria even when the salt concentration is reduced to levels typical of healthy lungs.

(E) The salt concentration in the airway-surface fluid of people whose lungs produce lower-than-average amounts of the antibiotic is generally much lower than that typical of healthy lungs.


A - Strengthening
B-2nd best answer: People with cystic fibroses, however, are unable to fight off such bacteria, even though their lungs produce normal amounts of the antibiotic.: Hence, No
C-Okay. Additional information not relevant to the question
D- Perfect . Answer
E-Out of scope of the question

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Re: Healthy lungs produce a natural antibiotic that protects them from inf   [#permalink] 19 Nov 2017, 03:27
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