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In large doses, analgesics that work in the brain as

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In large doses, analgesics that work in the brain as [#permalink]

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02 Jul 2009, 12:06
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In large doses, analgesics that work in the brain as antagonists to certain chemicals have caused psychological disturbances in patients, which may limit their potential to relieve severe pain.

(A) which may limit their potential to relieve
(B) which may limit their potential for relieving
(C) which may limit such analgesics’ potential to relieve
(D) an effect that may limit their potential to relieve
(E) an effect that may limit the potential of such analgesics for relieving

[Reveal] Spoiler:
E

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02 Jul 2009, 12:19
Quote:
In large doses, analgesics that work in the brain as antagonists to certain chemicals have caused psychological disturbances in patients, which may limit their potential to relieve severe pain.

(A) which may limit their potential to relieve - pronoun confusion and unidiomatic - potential to
(B) which may limit their potential for relieving - pronoun confusion
(C) which may limit such analgesics’ potential to relieve- unidiomatic - potential to
(D) an effect that may limit their potential to relieve - pronoun confusion and unidiomatic - potential to
(E) an effect that may limit the potential of such analgesics for relieving

E is correct
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02 Jul 2009, 12:25
"pronoun confusion" - very well done

is "potential to" unidiomatic?
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02 Jul 2009, 12:33
I am sorry - 'Potential to' is idiomatic
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02 Jul 2009, 12:49
I was debating between C and E. If I did not see the OA, honestly I would have picked C. (because I thought potential to is more idiomatic then potential for relieving..)

Not still sure why E is better than C. Might be the unnecessary usage of possessive (such analgesics' potential) is too wordy compared to the simple - 'limit the potential of such analgesics in E.

Any thoughts???
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02 Jul 2009, 12:57

Gmat prefers using verb + infinitive over using gerunds.

so "potential to relieve" should be better than "potential for relieving"

I agree about C, possessive clause for inanimate things is not encouraged in english.

As Vannu pointed out, E is probably best because "their" is confusing in all other options, it is not referring precisely to analgesics, "their" could also be used for "certain chemicals" here.
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03 Jul 2009, 07:39
"patients, which" immediately eliminate A, B and C.

"their" in D is unclear of refering to antagonists or patients.

E should be correct.
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03 Jul 2009, 08:17
Quote:
"patients, which" immediately eliminate A, B and C.

Why do you think we should eliminate A,B and C based on patients, which?
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03 Jul 2009, 09:49
vannu wrote:
Quote:
"patients, which" immediately eliminate A, B and C.

Why do you think we should eliminate A,B and C based on patients, which?

I think 'which' here refers to 'patients' and that's why these options are eliminated. Actually the discussion is about the effects of a particular drug.
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Re: Analgesics   [#permalink] 03 Jul 2009, 09:49
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