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# Macrophages are cells that play a role in the response of

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Macrophages are cells that play a role in the response of [#permalink]

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02 Sep 2006, 22:05
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66% (04:26) correct 34% (01:40) wrong based on 920 sessions

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Macrophages are cells that play a role in the response of the immune system of mice and other mammals to invasive organisms such as bacteria. Unlike other mice, mice that are genetically incapable of making these particular cells do not show elevated levels of nitrates when infected with bacteria.

The statements above, if true, provide the most support for which of the following conclusions?

A:Mice that are unable either to make macrophages or to make them in sufficient numbers will protect themselves from bacterial infections in some other way.

B:Mice that show elevated levels of nitrates can easily fight off most types of bacterial infections.

C:In mice, macrophages play a role in the production of nitrates or inhibit a process by which nitrates are broken down or otherwise eliminated.

D:When a healthy mouse becomes infected with an invasive organism, the number of macrophages in the mouseâ€™s body decreases.

E:Injections of nitrates into mice that lack macrophages will not enhance the ability of these animalsâ€™ immune systems to fight off infection.
[Reveal] Spoiler: OA

Last edited by pqhai on 07 Dec 2013, 22:51, edited 2 times in total.
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Re: CR-mice incapable of making macrophages [#permalink]

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03 Sep 2006, 03:32
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jerrywu wrote:
Mice that are genetically incapable of making macrophages do not show elevated levels of nitrates when infected with bacteria.

A:Mice that are unable either to make macrophages or to make them in sufficient numbers will protect themselves from bacterial infections in some other way.

B:Mice that show elevated levels of nitrates can easily fight off most types of bacterial infections.

C:In mice, macrophages play a role in the production of nitrates or inhibit a process by which nitrates are broken down or otherwise eliminated.

D:When a healthy mouse becomes infected with an invasive organism, the number of macrophages in the mouseâ€™s body decreases.

E:Injections of nitrates into mice that lack macrophages will not enhance the ability of these animalsâ€™ immune systems to fight off infection.

Clear C for me.
The conclusion is more about the nitrate production than about the defense mechanisms against bacterial infections.
No macrophage = no nitrate. C states that macrophages are involved in production of nitrates (positive role) or inhibition of nitrate break down (negative role).
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02 Sep 2006, 22:28
Took me almost three minutes to clarify the difference between B and C. C is a distortion of the premise to the the argument. All other answer choices are out of scope.

Best bet is (B)

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03 Sep 2006, 00:09
C for me.
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03 Sep 2006, 00:16
I go for C.

Second sentence suggests that Macrophages elevates the levels of nitrates and a lack of Macrophages will not elevate levels of nitrates.
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03 Sep 2006, 10:54
C here..
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03 Sep 2006, 11:10
One more C
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C for me as well [#permalink]

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03 Sep 2006, 14:31
C for me as well
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04 Sep 2006, 01:07
I am on the C bus
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04 Sep 2006, 05:37
defenestrate wrote:
I am on the C bus

I am on the C train...
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05 Sep 2006, 05:17
my answer is also B. What's the OA?
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05 Sep 2006, 17:30
I will go for B.

IMHO C seems to explain both positive and negative ways of nitrates production.
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05 Sep 2006, 18:30
I like C here... tough one though !
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11 Sep 2006, 18:59
No OA?
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11 Sep 2006, 19:04
anandsebastin wrote:
No OA?

Hello OA is (C)
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11 Sep 2006, 19:58
C.

I thought B was close too, I eliminated B because it uses "fight off most types of bacterial infections", which is extreme.

There was one more thing that bothered me, argument says "macrophages" plays role in providing immune system against bacterial infection, so nitrate level could just be a side effect and that doesn't mean when you high level of nitrate level, it can make "macrophages"
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Re: Macrophages are cells that play a role in the response of [#permalink]

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07 Dec 2013, 19:39
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Re: Macrophages are cells that play a role in the response of [#permalink]

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15 Dec 2014, 12:13
Hello from the GMAT Club VerbalBot!

Thanks to another GMAT Club member, I have just discovered this valuable topic, yet it had no discussion for over a year. I am now bumping it up - doing my job. I think you may find it valuable (esp those replies with Kudos).

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Re: Macrophages are cells that play a role in the response of [#permalink]

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26 Sep 2016, 17:44
Hello from the GMAT Club VerbalBot!

Thanks to another GMAT Club member, I have just discovered this valuable topic, yet it had no discussion for over a year. I am now bumping it up - doing my job. I think you may find it valuable (esp those replies with Kudos).

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Re: Macrophages are cells that play a role in the response of [#permalink]

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28 Sep 2016, 16:06
hi ChrisLele,

Re: Macrophages are cells that play a role in the response of   [#permalink] 28 Sep 2016, 16:06

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