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Frazier and Mosteller assert that medical research could be improved by a move toward larger, simpler clinical trials of medical treatments. Currently, researchers collect far more background information on patients than is strictly required for their trials-substantially more than hospitals collect-thereby escalating costs of data collection, storage, and analysis. Although limiting information collection could increase the risk that researchers will overlook facts relevant to a study, Frazier and Mosteller contend that such risk, never entirely eliminable from research, would still be small in most studies. Only in research on entirely new treatments are new and unexpected variables likely to arise.
Frazier and Mosteller propose not only that researchers limit data collection on individual patients but also that researchers enroll more patients in clinical trials, thereby obtaining a more representative sample of the total population with the disease under study. Often researchers restrict study participation to patients who have no ailments besides those being studied. A treatment judged successful under these ideal conditions can then be evaluated under normal conditions. Broadening the range of trial participants, Frazier and Mosteller suggest, would enable researchers to evaluate a treatment's efficacy for diverse patients under various conditions and to evaluate its effectiveness for different patient subgroups. For example, the value of a treatment for a progressive disease may vary according to a patient's stage of disease. Patients' ages may also affect a treatment's efficacy.
According to the passage, Frazier and Mosteller believe which of the following about medical research? A. It is seriously flawed as presently conducted because researchers overlook facts that are relevant to the subject of their research. B. It tends to benefit certain subgroups of patients disproportionately. C. It routinely reveals new variables in research on entirely new treatments. D. It can be made more accurate by limiting the amount of information researchers collect. E. It cannot be freed of the risk that significant variables may be overlooked.
The author mentions patients' ages primarily in order to A. identify the most critical variable differentiating subgroups of patients B. cast doubt on the advisability of implementing Frazier and Mosteller's proposals about medical research C. indicate why progressive diseases may require different treatments at different stages D. illustrate a point about the value of enrolling a wide range of patients in clinical trials E. substantiate an argument about the problems inherent in enrolling large numbers of patients in clinical trials
The passage is primarily concerned with A. identifying two practices in medical research that may affect the accuracy of clinical trials B. describing aspects of medical research that tend to drive up costs C. evaluating an analysis of certain shortcomings of current medical research practices D. describing proposed changes to the ways in which clinical trials are conducted E. explaining how medical researchers have traditionally conducted clinical trials and how such trials are likely to change
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Re: Frazier and Mosteller assert that medical research could be
[#permalink]
18 Feb 2005, 00:07
1. According to the passage, Frazier and Mosteller believe which of the following about medical research?
D. It can be made more accurate by limiting the amount of information researchers collect.
2. The author mentions patients' ages primarily in order to
D. illustrate a point about the value of enrolling a wide range of patients in clinical trials
3. The passage is primarily concerned with
D. describing proposed changes to the ways in which clinical trials are conducted
Re: Frazier and Mosteller assert that medical research could be
[#permalink]
18 Feb 2005, 09:54
1. B
Frazier and Mosteller assert that medical research could be improved but 'D' mentions it can be made more accurate so 'D' can be eliminated.
2. D
3. C
Frazier and Mosteller are proposing changes they are not describing somebody else's proposal so 'D' can be elimianted
Re: Frazier and Mosteller assert that medical research could be
[#permalink]
19 Feb 2005, 07:11
I got them as (1)D (2)D (3)D
(1)After reading the first paragraph, I could gather that limiting information helps in conducting better research. A, B, C and E donot mention about it. Only D addresses the issue.
(2)For the 2nd, I was torn between C and D. And I chose D finally.
(3) D because the whole passage describes what F & M think about clinical trials.
rahul wrote:
Frazier and Mosteller assert that medical research could be improved by a move toward larger, simpler clinical trials of medical treatments. Currently, researchers collect far more background information on patients than is strictly required for their trials-substantially more than hospitals collect-thereby escalating costs of data collection, storage, and analysis. Although limiting information collection could increase the risk that researchers will overlook facts relevant to a study, Frazier and Mosteller contend that such risk, never entirely eliminable from research, would still be small in most studies. Only in research on entirely new treatments are new and unexpected variables likely to arise.
Frazier and Mosteller propose not only that researchers limit data collection on individual patients but also that researchers enroll more patients in clinical trials, thereby obtaining a more representative sample of the total population with the disease under study. Often researchers restrict study participation to patients who have no ailments besides those being studied. A treatment judged successful under these ideal conditions can then be evaluated under normal conditions. Broadening the range of trial participants, Frazier and Mosteller suggest, would enable researchers to evaluate a treatment's efficacy for diverse patients under various conditions and to evaluate its effectiveness for different patient subgroups. For example, the value of a treatment for a progressive disease may vary according to a patient's stage of disease. Patients' ages may also affect a treatment's efficacy.
According to the passage, Frazier and Mosteller believe which of the following about medical research? A. It is seriously flawed as presently conducted because researchers overlook facts that are relevant to the subject of their research. B. It tends to benefit certain subgroups of patients disproportionately. C. It routinely reveals new variables in research on entirely new treatments. D. It can be made more accurate by limiting the amount of information researchers collect. E. It cannot be freed of the risk that significant variables may be overlooked.
The author mentions patients' ages primarily in order to A. identify the most critical variable differentiating subgroups of patients B. cast doubt on the advisability of implementing Frazier and Mosteller's proposals about medical research C. indicate why progressive diseases may require different treatments at different stages D. illustrate a point about the value of enrolling a wide range of patients in clinical trials E. substantiate an argument about the problems inherent in enrolling large numbers of patients in clinical trials
The passage is primarily concerned with A. identifying two practices in medical research that may affect the accuracy of clinical trials B. describing aspects of medical research that tend to drive up costs C. evaluating an analysis of certain shortcomings of current medical research practices D. describing proposed changes to the ways in which clinical trials are conducted E. explaining how medical researchers have traditionally conducted clinical trials and how such trials are likely to change
Re: Frazier and Mosteller assert that medical research could be
[#permalink]
07 Dec 2011, 11:41
E D D FOR NUMBER 1, THE AUTHOR DID NOT MENTION ANYWHERE IN THE PASSAGE THAT D.It can be made more accurate by limiting the amount of information researchers collect.
Re: Frazier and Mosteller assert that medical research could be
[#permalink]
17 Apr 2012, 11:28
carlosdop wrote:
FOR NUMBER 1, THE AUTHOR DID NOT MENTION ANYWHERE IN THE PASSAGE THAT D.It can be made more accurate by limiting the amount of information researchers collect.
I disagree. Read the very first line in the passge,
Frazier and Mosteller assert that medical research could be improved by a move toward larger,
The question is about what Frazier and Mosteller believe, not the author.
Re: Frazier and Mosteller assert that medical research could be
[#permalink]
18 Apr 2012, 09:03
rahul wrote:
Frazier and Mosteller assert that medical research could be improved by a move toward larger, simpler clinical trials of medical treatments. Currently, researchers collect far more background information on patients than is strictly required for their trials-substantially more than hospitals collect-thereby escalating costs of data collection, storage, and analysis. Although limiting information collection could increase the risk that researchers will overlook facts relevant to a study, Frazier and Mosteller contend that such risk, never entirely eliminable from research, would still be small in most studies. Only in research on entirely new treatments are new and unexpected variables likely to arise.
Frazier and Mosteller propose not only that researchers limit data collection on individual patients but also that researchers enroll more patients in clinical trials, thereby obtaining a more representative sample of the total population with the disease under study. Often researchers restrict study participation to patients who have no ailments besides those being studied. A treatment judged successful under these ideal conditions can then be evaluated under normal conditions. Broadening the range of trial participants, Frazier and Mosteller suggest, would enable researchers to evaluate a treatment's efficacy for diverse patients under various conditions and to evaluate its effectiveness for different patient subgroups. For example, the value of a treatment for a progressive disease may vary according to a patient's stage of disease. Patients' ages may also affect a treatment's efficacy.
According to the passage, Frazier and Mosteller believe which of the following about medical research? A. It is seriously flawed as presently conducted because researchers overlook facts that are relevant to the subject of their research. B. It tends to benefit certain subgroups of patients disproportionately. C. It routinely reveals new variables in research on entirely new treatments. D. It can be made more accurate by limiting the amount of information researchers collect. E. It cannot be freed of the risk that significant variables may be overlooked.
The author mentions patients' ages primarily in order to A. identify the most critical variable differentiating subgroups of patients B. cast doubt on the advisability of implementing Frazier and Mosteller's proposals about medical research C. indicate why progressive diseases may require different treatments at different stages D. illustrate a point about the value of enrolling a wide range of patients in clinical trials E. substantiate an argument about the problems inherent in enrolling large numbers of patients in clinical trials
The passage is primarily concerned with A. identifying two practices in medical research that may affect the accuracy of clinical trials B. describing aspects of medical research that tend to drive up costs C. evaluating an analysis of certain shortcomings of current medical research practices D. describing proposed changes to the ways in which clinical trials are conducted E. explaining how medical researchers have traditionally conducted clinical trials and how such trials are likely to change
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Re: Frazier and Mosteller assert that medical research could be [#permalink]
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