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805+ Level|   Math Related|            
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AAA, CCC , GGG, UUU
Total ways of arranging= 12!/(3!)^4

1) AAA + {CCCGGGUUU}=4C3*9!/(3!)^3
P=4C3*9!/(3!)^3 / 12!/(3!)^4=1/55

2) ACG +{AACCGGUUU}=4C3 3! 9!/((2!)^3.3!)
P=4C3 3! 9!/((2!)^3.3!)/12!/(3!)^4=27/55
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There seems to be a typo in "two of other 3 types =
4C3∗3!∗9!/3!2!2!"
chetan2u

guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.
­Each RNA sequence will be made from A,A,A,C,C,C,G,G,G,U,U, and U.

Total ways of arranging, say n things, when x are similar, y are similar and of another type: n!/x!y!
We divide by x! and y! as these similar items can be arranged within themselves in x! and y! ways, and taking them separately gives repetitions.

Total ways = \(\frac{12!}{3!3!3!3!} \)

(I) First 3 nucleobases are all of the same type: So, first three places can be taken by any of the four, so 4 ways, while remaining 9 places can be filled by other 3 types = \(\frac{4*9!}{3!3!3!}\)
P =\( \frac{\frac{4*9!}{3!3!3!}}{\frac{12!}{3!3!3!3! }}= \frac{4*3!}{12*11*10 }= \frac{1}{55}\)­

(II) First 3 nucleobases are of three different types: So, first three places can be taken by any three of the four, so 4C3 ways or 4C3*3! when arranged, while remaining 9 places can be filled by three of one kind and two of other 3 types = \(\frac{4C3*3!*9!}{3!2!2!}\)
P =\( \frac{\frac{4!*9!}{3!2!2!2!}}{\frac{12!}{3!3!3!3! }}= \frac{4!*3*3*3}{12*11*10 }= \frac{27}{55}\)­
­
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Hi Purnank, could you please elaborate & explain what those numbers represent/how you solved this? Your method seems the fastest
Purnank
guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
­ all of the same type = \(\frac{4C1*3C3}{12C3}=\frac{1}{55}\)

3 different types = \(\frac{4C3*3C1*3C1*3C1}{12C3} = \frac{27}{55}\)­
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See here we have 4 different types.
When all are same that means we have to select one type from 4 so 4C1
and when all are different means we have to select 3 from group of 4 so 4C3
anything else you need?
jdoe123
Hi Purnank, could you please elaborate & explain what those numbers represent/how you solved this? Your method seems the fastest
Purnank
guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
­ all of the same type = \(\frac{4C1*3C3}{12C3}=\frac{1}{55}\)

3 different types = \(\frac{4C3*3C1*3C1*3C1}{12C3} = \frac{27}{55}\)­
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We are choosing 3 nucleobases from a total of 12, with exactly 3 of each type. The total number of ways to choose any 3 nucleobases from 12 is:
\(12C3\) = \(\frac{ 12!}{10!* 2!}\)

Case 1 - Probability that all 3 nucleobases are the same
  • The RNA has 4 types of nucleobases: A, C, G, and U.
  • There are exactly 3 of each type in the sequence.
So, the possible choices for picking 3 identical nucleobases are:
  • AAA (All Adenine)
  • CCC (All Cytosine)
  • GGG (All Guanine)
  • UUU (All Uracil)

Hence, 4 ways.
So, Probablity that all 3 nucleobases being the same:
= \(\frac{ 4}{12!/(10!* 2!)}\)

= \(\frac{1}{55}\)

Case 2 - Probability that all 3 nucleobases are different
[*]There are 4 types of nucleobases, so we are choosing 3 out of 4.
[*]The number of ways to choose which 3 types we pick from 4 is:

\(4C3\) =4
[*]Once we have chosen which 3 types, we must pick 1 nucleobase from each of those 3 types.
[*]Since each type has 3 choices, the number of ways to do that is:

\(3×3×3=27\)

So, Probability that all 3 nucleobases are different:

= \(\frac{4*27}{12!/(10!* 2!)}\)

= \(\frac{27}{55}\)
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karishma could you please share how to approach this?
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-> The 12 nucleobases -> (AAA) (GGG) (CCC) (UUU)
-> Collection of all possible sequences consisting of the above 12 nucleobases means all possible arrangements of the above.

How many different arrangements of the 12 nucleobases are possible?

\(\frac{12! }{ 3! 3! 3! 3!}\)

-> One particular sequence (out of the above possible ones) will be selected, and the first 3 nucleobases (for instance, ACG, or AAU) will be detached.

-> Probability that the 3 detached nucleobases are all of the same type

In other words, what is the probability that out of all the possible sequences, the sequence selected was one where the first 3 nucleobases were all of the same type?

(1) Total number of possible sequences = \(\frac{12! }{ 3! 3! 3! 3!}\)

Number of arrangements where the first 3 nucleobases are all of the same type

- First, select the 1 type out of 4 (A,C,G,U) which will form the first 3 nucleobases (e.g. - AAA, or UUU) -> 4C1. There is only one way to arrange these 3 (XXX is one arrangement).
- Now, for the remaining 9 nucleobases, we have a total of \(\frac{9! }{ 3! 3! 3!}\) arrangements.

(2) Number of favorable sequences = \(\frac{4C1 * 9! }{ 3! 3! 3!}\)

P(All the same type) = (2) / (1) = 1/55

-> Probability that the 3 detached nucleobases are of 3 different types

In other words, what is the probability that out of all the possible sequences, the sequence selected was one where the first 3 nucleobases were of 3 different types (Say, AGC, or UAG)?

- First, out of 4 types (A,C,G,U), select the 3 which will be used to form the first 3 nucleobases -> 4C3
- How many arrangements of these 3 are possible? 3!
- Now, for the remaining 9 nucleobases, we have 2 each of the 3 types which were used above and all 3 of the unused type (2,2,2,3).
- Number of arrangements of the 9 nucleobases possible -> \(\frac{9! }{ 2! 2! 2! 3!}\)

(3) Number of favorable sequences = \(\frac{4C3 * 3! * 9! }{ 2! 2! 2! 3!}\)

P(3 different types) = (3) / (1) = 27/55.
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How are you supposed to solve this in about 2 mins? karishma
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guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
Just adding a faster method ...

There are three of each type, so in total 12 nucleobases say A1, A2, A3, B1, B2......U3.

1) All three are of same type..

Choose any of 3 As from A1, A2, and A3...So 3C3 or 1 way..
Similarly 1 way for each of Cs, Gs and Us.
Thus total 4 ways.. and each such selection can be arranged in 3! ways
Total ways = 12*11*10

P = 4*3*2/12*11*10 or 1/55


2) All three are different

Choose any of the 12 (say A) for first place.
Next leaving out that (A) here, choose from remaining 9, say C here
Finally choose from 6 of Gs and Us left..
Total 12*9*6
Total ways 12*11*10

P = 12*9*6/12*11*10 = 27/55
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Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­


All the same type

probability of 1 way of getting all of 1 type × ways to do that =

(3/12 × 2/11 × 1/10) × 4 = 1/55

3 different types

probability of 1 way of getting 3 different types × ways to do that =

(3/12 × 3/11 × 3/10) × (4c3 × 3p3) = 27/55

Correct answer: 1/55, 27/55
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Can you please elaborate,

Choose any of 3 As from A1, A2, and A3...So 3C3 or 1 way..
Similarly 1 way for each of Cs, Gs and Us.
Thus total 4 ways.. and each such selection can be arranged in 3! ways

From this step how did u know total ways = 12 * 11 *10

Thanks!!
chetan2u
guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
Just adding a faster method ...

There are three of each type, so in total 12 nucleobases say A1, A2, A3, B1, B2......U3.

1) All three are of same type..

Choose any of 3 As from A1, A2, and A3...So 3C3 or 1 way..
Similarly 1 way for each of Cs, Gs and Us.
Thus total 4 ways.. and each such selection can be arranged in 3! ways
Total ways = 12*11*10

P = 4*3*2/12*11*10 or 1/55


2) All three are different

Choose any of the 12 (say A) for first place.
Next leaving out that (A) here, choose from remaining 9, say C here
Finally choose from 6 of Gs and Us left..
Total 12*9*6
Total ways 12*11*10

P = 12*9*6/12*11*10 = 27/55
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Total ordered draws of 3 distinct nucleobases out of 12 is
12*11*10 = 12P3 = 1320.

All three the same type:
  • Pick which letter (A, C, G or U): 4 ways,
  • Then there’s exactly one way to choose all three of its copies,
  • But those three can appear in any order: 3! = 6 ways.
  • So favorable ordered triples = 4*6 = 24

Probability
\(\frac{24}{1320}\) = \(\frac{1}{55}\)
bhanu29
Can you please elaborate,

Choose any of 3 As from A1, A2, and A3...So 3C3 or 1 way..
Similarly 1 way for each of Cs, Gs and Us.
Thus total 4 ways.. and each such selection can be arranged in 3! ways

From this step how did u know total ways = 12 * 11 *10

Thanks!!
chetan2u
guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
Just adding a faster method ...

There are three of each type, so in total 12 nucleobases say A1, A2, A3, B1, B2......U3.

1) All three are of same type..

Choose any of 3 As from A1, A2, and A3...So 3C3 or 1 way..
Similarly 1 way for each of Cs, Gs and Us.
Thus total 4 ways.. and each such selection can be arranged in 3! ways
Total ways = 12*11*10

P = 4*3*2/12*11*10 or 1/55


2) All three are different

Choose any of the 12 (say A) for first place.
Next leaving out that (A) here, choose from remaining 9, say C here
Finally choose from 6 of Gs and Us left..
Total 12*9*6
Total ways 12*11*10

P = 12*9*6/12*11*10 = 27/55
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Elaborating on @Purnank's method, as I just understood it:

1. When all 3 are of the same type

There are 4C1 ways of selecting a type out of 4 total (A, C, G, U). From that type, there are 3 units of each, so 3C3.
Total number of ways we could select any 3 is 12C3.

\(\frac{4C1*3C3}{12C3}=\frac{1}{55}\)

2. When 3 are of different types

Here, you are selecting 3 types out of the 4, so 4C3, and one unit from each of the 3 units for that specific type.

\(\frac{4C3*3C1*3C1*3C1}{12C3} = \frac{27}{55}\)­

jdoe123
Hi Purnank, could you please elaborate & explain what those numbers represent/how you solved this? Your method seems the fastest
Purnank
guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
­ all of the same type = \(\frac{4C1*3C3}{12C3}=\frac{1}{55}\)

3 different types = \(\frac{4C3*3C1*3C1*3C1}{12C3} = \frac{27}{55}\)­
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hey can anyone help me out with choosing the answer from the correct column. i got the answer right but i got messed up in choosing the column in the first one it was A. and and second it was last one so i did exactly opposite i get confused .....
guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
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The process for finding each answer is fairly different so did you not read the columns or how did you get them mixed up?
HRX273
hey can anyone help me out with choosing the answer from the correct column. i got the answer right but i got messed up in choosing the column in the first one it was A. and and second it was last one so i did exactly opposite i get confused .....
guddo
­Ribonucleic acid (RNA) is a molecule built from sequences of smaller molecules called nucleobases. RNA nucleobases are of 4 different types: adenine (A), cytosine (C), guanine (G), and uracil (U). Consider the collection of all possible RNA sequences consisting of 12 nucleobases, 3 of each type. An RNA sequence will be selected at random from this collection, and the first 3 nucleobases of the sequence will be detached from the sequence.

In the table, select the probability that the 3 nucleobases are all of the same type, and select the probability that they are of 3 different types. Make only two selections, one in each column.­

ID: 101100
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I like the solution, its helpful.
tHANKS
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