The answer is A.
The question doesn't say that each prime digit can only appear once,
so there are |{2,3,5,7}|^4 = 4^4 = 256 possibilities beginning with
2222 and ending with 7777.
Much more difficult is determining the numbers that are divisible
by 12. A number is divisible by 12 if it's divisible by both 3 and 4.
So we can through the combinations where the checksum isn't
divisible by 3 and where the last 2 digits aren't divisible by 4
(which means that the whole number is divisible by 4).
Remaining are the following numbers satisfying the given condition:
2232
2352
2532
2772
3252
3372
3552
3732
5232
5352
5532
5772
7272
7332
7572
7752
Since these are 16 numbers, the answer to the question is
16/256 = 1/16 --> A.
But I guess very few could solve this in about 2 minutes (I didn't)