The answer is E.
(A) from Macon to Omaha, during which the business
This option introduces the phrase "during which" to describe the time frame of the relocation. However, it creates an awkward construction and doesn't maintain concise and clear expression.
(B) from Macon to Omaha, where it
This choice uses the pronoun "it" to refer to the business. While the sentence is clear, the use of "it" might lead to some ambiguity as to what "it" refers to. There could be a slight lack of clarity regarding the subject.
(C) from Macon to Omaha, where they
The use of "they" lacks a clear antecedent in this sentence. It creates confusion as to what "they" refers to in the context, leading to an ambiguous construction.
(D) it was then moved from Macon to Omaha, where it
This option introduces a passive voice ("it was then moved") which makes the sentence less direct and slightly convoluted.
(E) from Macon to Omaha, where the business
This option specifies "the business" explicitly, providing a clear and unambiguous reference to what moved from Macon to Omaha. It maintains conciseness while avoiding any potential ambiguity regarding the subject.