I'll go with
(D)
(A) Eye examinations provide more detailed information today than they did 35 years ago. - Irrelevant
(B) Doctors can establish that changes in eye pressure directly affect the cardiovascular system. - Strengthens rather than weakening the argument.
(C) Evidence other than eye pressure has previously enabled doctors to predict impending heart attacks that are predictable on the basis of information from opthamologists. -
information from opthalmologists may not necessarily mean information on eye pressure. Any kind of info might come from an opthalmologist, which might include the percentage of sugar (which might be detected by symptoms of glucomia) and might affect the cardiovascular system. This, however, does not weaken the argument.
(D) Doctors have not determined why changes in pressure on the eye fluctuate. - If doctors are not sure why the eye pressure changes, they cannot say for sure that an increase in eye pressure might result in cardio-vascular complications or vice-versa. Therefore, given this fact is true, it would lend less credibility to the claim that heart attacks can be predicted based on a certain patter of changes in the eye pressure.
(E) It has been established that predictable pressure patterns yield predictable pattern of medical symptoms. - ruled out again.