First of all, it's important not to read too much into the diagram.
All we can glean from the diagram is that we have a quadrilateral that is inscribed in the circle.
That's it!
So, first recognize that the inscribed quadrilateral COULD be a very very very narrow rectangle like this.

Notice that this quadrilateral COULD be so thin that its area is very very close to zero.
So, for this particular quadrilateral we get:
Quantity A: a very very small area that's close to zero
Quantity B: 40
In this case,
Quantity B is greater.
Alternatively, we COULD make the quadrilateral quite large.
In fact, we could make it a SQUARE.

So, if the inscribed quadrilateral is a square, what is its area?
To find out, let's draw a diagonal.

One of our circle properties tells us that this diagonal must be the diameter of the circle, which we know is 10
To find the area of the square, we need to know the length of each side.
So, let's let x = the length of each side.
Since ACD is a RIGHT TRIANGLE, we can apply the Pythagorean Theorem to get: x² + x² = 10²
Simplify to get 2x² = 100
Divide both sides by 2 to get:
x² = 50This means the area of the square =
50We know this because the area of the square = (x)(x) = x², and we just learned that
x² = 50So, for this particular quadrilateral we get:
Quantity A:
50Quantity B: 40
In this case,
Quantity A is greater.
Answer: D