Well, unless you've been working at McDonalds as the Fry Guy since you graduated, your resume can usually be worked to show your best accomplishments. In my experience, people often have gems in their record that they may not even recognize.
As an example, right after college I was hired to run a movie theater. Not a glamorous post, and hardly impressive in many people's eyes. Yet in eleven years with that company (and four locations of increasing responsibility), I won numerous awards for professional standards and success, and my skill set included doing my ow hiring and training, my own ADP payroll, analyzing my cash flow and product performance and ordering my own concession inventory, bidding for films, auditing other managers' operations and preparing my own P&L statements to figure out in advance what would happen to my next year's budget.
When I plugged all that into my resume, my profile took on a distinctly superior polish, and every word of it is true.
Ten years of work is bound to show some sort of accomplishment; focus on that.