IMO B
Let say none of the no. Is subtracted and is added onto one another.
The absolute sum is 78
So option E can never be the choice.
Option D = 77 (78-1) But we need a pair of two to determine one. Let say 2-1=1 but the changes in 78 will be like 78-2-1+1=76. Option D not possible.
Option C = 65 (78-13)
Let say 12+1=13 is subtracted from whole. But, the operation won't be just 78-13. The no. 1&12 won't be added to the sum as well.
So (2+3)+(4+5)+(6+7)+(8+9)+(10+11)-(12+1)
=52 ((option C out))
(Moreover the pair
Option A = 43 (78-35)
Just like option C just 35 can't be minus. (It can be (1+3)+(4+5)+(6+7)+(8+9)-(11+12)+(10+2)
It will be 78-35-35 that is 8. Not possible
(We can see a multiple of two us always deducted from the total to drive value and C And A were lacking that)
Option B = 50 (78-28)
28 is an even no. (-14-14)
The operation can be
(1+3)+(4+5)+(6+7)+(8+9)+{(10+11)-(12+2)}
= 50 (answer)
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