Scientists have recently discovered that, in doses massive enough to kill cells, almost any chemical is carcinogenic because cell death causes rapid division among surviving cells, promoting cancer-causing mutations. A few chemicals are also carcinogenic without causing cell death. Until now studies of the carcinogenicity of food additives have always involved administering to test animals doses of additives larger than the largest possible human exposure levels and massive enough to kill large numbers of cells in the animals, and then observing the animals' cancer rates.
If the statements above are true, which one of the following conclusions is most strongly supported by them?The passage says past tests used extremely large doses that killed many cells, and cell death itself can make almost any chemical appear carcinogenic.
So past studies may have made some additives look more dangerous than they would be at realistic human exposure levels.(A) In the doses heretofore used in carcinogenicity studies of food additives, cell death often does not occur in test animals.
Wrong. The passage says those doses were massive enough to kill large numbers of cells.
(B) Until now results of carcinogenicity studies encouraged overestimation of the degree to which some food additives are carcinogenic.
Correct. Since the test doses caused cell death, and cell death can itself promote cancer-causing mutations, some additives may have appeared carcinogenic because of the unrealistically massive dose, not because they would be carcinogenic under
normal human exposure.
(C) Truly carcinogenic chemicals usually cause some immediate cell death, even in small doses.
Wrong. The passage says a few chemicals are carcinogenic without causing cell death, but it does not say truly carcinogenic chemicals usually cause cell death in small doses.
(D) Carcinogenic chemicals are usually absorbed in small doses in the natural environment.
Wrong. The passage says nothing about absorption in the natural environment.
(E) Most of the food additives that are now banned because of carcinogenicity could safely be used in human foods.
Wrong. Too strong. The passage supports possible overestimation in some cases, not that most banned additives are safe.
Answer: (B)