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My Understanding...

All choices other than B either weaken the conclusion or are Out of Scope

By eliminating Regional factor as the cause for Variation (as mentioned in the argument), it strengthens ‘unnecessary prescription of drugs’ as cause for variations
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gmatbull
The rate at which psychiatrists in different regions administer many prescription drugs shows massive variation — up to a fifty-fold dissimilarity per million patients in the numbers of antidepressant, anti-bipolar, and anti-psychotic medications prescribed.

To support a conclusion that much of the variation is due to unnecessary prescription of drugs, it would be necessary to establish which of the following?

A: Every psychiatrist is supervised by a regional review board, which checks the record of every patient to confirm that the prescription drug was necessary.

B: The dissimilarity is unrelated to regional factors (other than the prescription drugs themselves) that influence the incidence of diseases for which prescription drugs might be considered.

C: There are several classes of prescription drugs (other than antidepressant, anti-bipolar, and anti-psychotic ones) that are often administered unnecessarily.

D: For certain prescription drugs, it is difficult to determine after the treatment whether the drug was necessary or whether an alternative treatment would have been effective.

E: The prescribing of antidepressant, anti-bipolar, and anti-psychotic drugs is representative of prescription drugs generally with respect to how often they are prescribed unnecessarily.

Between A and B here. But went with A cause it sounded more straightforward. Will anybody dare to share direct comparison between those two answer choices?

Thanks!
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gmatbull
The rate at which psychiatrists in different regions administer many prescription drugs shows massive variation — up to a fifty-fold dissimilarity per million patients in the numbers of antidepressant, anti-bipolar, and anti-psychotic medications prescribed.

To support a conclusion that much of the variation is due to unnecessary prescription of drugs, it would be necessary to establish which of the following?

A: Every psychiatrist is supervised by a regional review board, which checks the record of every patient to confirm that the prescription drug was necessary.

B: The dissimilarity is unrelated to regional factors (other than the prescription drugs themselves) that influence the incidence of diseases for which prescription drugs might be considered.

C: There are several classes of prescription drugs (other than antidepressant, anti-bipolar, and anti-psychotic ones) that are often administered unnecessarily.

D: For certain prescription drugs, it is difficult to determine after the treatment whether the drug was necessary or whether an alternative treatment would have been effective.

E: The prescribing of antidepressant, anti-bipolar, and anti-psychotic drugs is representative of prescription drugs generally with respect to how often they are prescribed unnecessarily.

TO SUPPORT THE conclusion that much of the variation is due to unnecessary prescription of drugs, WE WOULD LIKE TO ESTABLISH THAT THERE WERE NO OTHER REASON FOR VARIATION IN QUANTITY OF PRESCRIPTION OTHER THAN UNNECESSARY PRESCRIPTION.....B CORRECTLY RULES OUT REGIONAL FACTORS.....
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Can someone explain the meaning of E and why is it incorrect?
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yes, I second that, can someone explain why its not E?
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nycgirl212
yes, I second that, can someone explain why its not E?

The conclusion that needs support is that unnecessary prescription of psychiatric medication at certain regions has caused vast variation in different regions. Therefore the answer must have a statement that correlates regions and psychiatric drugs.

Option E points at a relation between psychiatric prescription drugs and all prescription drugs. However this option does not point at any correleation between regions and psychiatric drugs.

Hence option E is irrelevant.
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