Presolar grains, which may be older than our solar system, are much like ordinary meteorite fragments, but their chemical composition is different than any typical extraterrestrial mineral; they contain trace amounts of helium and neon and slightly less silicon carbide than the average meteor does.
(A) is different than any typical extraterrestrial mineral; they contain
“different than any” is unidiomatic
(B) is different than any typical extraterrestrial mineral’s, containing
“different than any” is unidiomatic
(C) is different from that of any typical extraterrestrial mineral; they contain
Correct: “different from” is correct and “that of” also correctly refers to “composition”. Semicolon used correctly to start a new clause.
(D) differs from any typical extraterrestrial mineral in containing
Incorrect comparison: composition is compared with minerals, not with their composition
“in containing” changes the intended meaning.
(E) differs from that of any typical extraterrestrial mineral, containing
“containing” refers to the closest action “are different” and thus makes the sentence illogical because now it means that A is different by containing X. hence out.
Hence C