A. the leaders of the Human Genome Project not to hold a convention in the center opposite the local church since the agenda presented in the convention may be offensive to
them--> "Them" may also refer back to the "leaders of the Human Genome Project" hence unclear antecedent
B. the leaders of the Human Genome Project not to hold a convention at the local church since the agenda presented in the convention may be offensive to
them--> "Them" may also refer back to the "leaders of the Human Genome Project" hence unclear antecedent
--> the sentence also references only the "local church" and not the "opposite local church"
C. the leaders of the Human Genome Project not to hold a convention in the center opposite the local church due to the fact that the agenda presented in the convention may be offensive to
them.
--> "Them" may also refer back to the "leaders of the Human Genome Project" hence unclear antecedent
D. the leadership of the Human Genome Project not to hold a convention in the center opposite the local church due to the
fact the agenda presented in the convention may be offensive to them
--> due to the fact" should be followed by "that".
--> the leadership makes the pronoun "them" clear for the Churchgoers
E. the leadership of the Human Genome Project not to hold a convention in the center opposite the local church since the agenda presented in the convention may be offensive to them
--> the leadership makes the pronoun "them" clear for the Churchgoers
Option E