Last year, the United States introduced compulsory vaccination for all children of a certain age against rotavirus. Without the vaccination, rotavirus hospitalized 55,000 to 70,000 children in the United States per year; this year, the number of hospitalizations has been reduced by 20%. Based on this data, the Center for Disease Control (CDC) estimates that the rotavirus vaccine prevents more than 50,000 doctor visits per year.
Which of the following, if true, casts the most doubt on the estimate prepared by the CDC?
A) A 2-year-old child is much more susceptible to attacks by rotavirus than a five year old child.
B) Not all children affected by rotavirus go to the doctor.
C) Generally, a patient affected by rotavirus has a weaker than normal immune system and thus is more susceptible to other diseases.
D) The vaccine for Zetavirus, which also affects children of the same age as rotavirus does, prevents no more than 10,000 doctor visits per year.
E) Rotavirus vaccine is administered to 2 year old children and rotavirus attacks children above the age of four.