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C.

We need who after athletes NOT that. due to in the beginning doesn't makes sense. Hence, went w/ C. OA plz....
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It's between D and E. I eliminated D because of "who due to injury"

What's the OA?
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As a result of advances in biomedical engineering, many athletes that might at one time have lost their ability to participate in their sports due to catastrophic injury now can pursue their sports again, even if not as professionals.

that might at one time have lost their ability to participate in their sports due to catastrophic injury
that due to catastrophic injury might once have lost their ability to participate in their sports
who might once have lost their ability to participate in their sports due to catastrophic injury
Here 'due to' is substituting "attributable to". ....to participate in their sports 'attributable to' catastrophic injury.
who due to catastrophic injury might have at one time lost their ability to participate in their sports
who, due to catastrophic injury, might at one time have lost their ability to participate in their sports


I choose C.



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