Correct option A
Despite the doubts expressed by most physicians,
- Despite is used to highlight contrast opinionthe theory that
people ought to vary their diet
based in large part on their blood type- that usage (correct)
- the theory, based in (correct idioms)has won many new adherents in recent years.
- has : singular, the theory : singularOther option are wrong, reasons are :
B. determined by their blood type for the most part
-
determined is adjective modify blood type, which is noun, doesn't indicate a cause or reason, even if we consider
determined as verb, it will be in past tense and
"determine to" would be correct idiom than
determine byC. owing to their blood type
- owing to (phrase) means
yet to be paid to?
D. in large part in accordance with their blood type
-
in accordance with is
agree with X by Y with, we need cause and effect indicator not the comparison indicator.
- Phrases refer to verb without verb
in large part
in accordance withE. because in large part of their blood type
- "
Because of" implies that the decision was prompted by the analysis, whereas "
based on" means the decision was influenced by the analysis.