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OE for reference:

Overview: This passage recounts an experiment and the conclusion drawn by the experimenters. The experiment showed that, compared to nonhyperactive adults, hyperactive adults had much less brain activity in a region of the brain believed to control action. The experimenters concluded that this abnormality in the brains of hyperactive adults is one cause of hyperactivity.

The question asks what would undermine this conclusion. The only thing the experiment firmly establishes is a correlation between hyperactivity and diminished activity in a certain region of the brain. The experimenters' conclusion is one possible explanation for that correlation. So anything that points to an alternative explanation of the observed correlation would undermine the experimenters' conclusion.

The Correct Answer:

D (D) tells us that the differences in brain activity found in the experiment could well have been caused by the medication taken by the hyperactive adults but not by the nonhyperactive adults. So (D) points to an explanation of the experimental results that gives us a clear alternative to the conclusion that the experimenters reached.

The Incorrect Answer Choices:

A The experimenters' conclusion was based on tests performed on hyperactive and nonhyperactive adults. Information about the children of any of these adults has no bearing on what can be concluded from those tests.

B Variation in the severity of symptoms of hyperactivity would be expected in any random sample of hyperactive people. (B) gives us no reason to think that the experimenters had any difficulty in clearly distinguishing between adults who were hyperactive and those who were not. So (B) does nothing to challenge the experiment and thus does nothing to undermine the conclusion based on it.

C As long as an experiment was competently carried out, it makes no difference to the outcome whether the people who actually designed the experiment were present or not. (C) provides no reason to think that the experiment was not competently carried out. Thus (C) does nothing to undermine the conclusion based on the outcome of that experiment.

E (E) explains why the experimental subjects were all adults. It does not call into question the reliability of the results obtained by the experiment. Nor does it challenge the conclusion based on those results.
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