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07 Nov 2023, 02:30
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B
Be sure to select an answer first to save it in the Error Log before revealing the correct answer (OA)!
Difficulty:
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66% (02:13) correct
34%
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Mice treated with certain statins intended to decrease blood pressure also experienced drug-induced toxic myopathy, also known as muscular degeneration. Scientists hypothesize that this may have occurred because the statins cause an over-activation of creatine kinases, which are known to cause muscular degeneration.
Which of the following experiments would yield the most useful results for analyzing the scientists’ hypothesis?
A. Administering statins to mice with increased creatine kinase activity and observing creatine kinase activity.
B. Injecting mice with a creatine kinase inhibitor before administering the statins and then monitoring muscle tissue response.
C. Injecting mice with creatine kinase inhibitors and then monitoring muscle tissue response.
D. Injecting mice with muscle repair medication and then monitoring levels of muscular response.
E. Measuring mice’s level of muscular myopathy, administering a creatine kinase inhibitor, and then measuring myopathy once more
Which of the following experiments would yield the most useful results for analyzing the scientists’ hypothesis?
A. Administering statins to mice with increased creatine kinase activity and observing creatine kinase activity.
B. Injecting mice with a creatine kinase inhibitor before administering the statins and then monitoring muscle tissue response.
C. Injecting mice with creatine kinase inhibitors and then monitoring muscle tissue response.
D. Injecting mice with muscle repair medication and then monitoring levels of muscular response.
E. Measuring mice’s level of muscular myopathy, administering a creatine kinase inhibitor, and then measuring myopathy once more
07 Nov 2023, 04:44
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Imo Option B would yield the most useful results because it directly tests the hypothesis. By injecting a creatine kinase inhibitor before administering the statins, scientists can observe whether the inhibition of creatine kinase activity reduces the incidence or severity of the muscle tissue response. If the mice exhibit less muscular degeneration with the inhibitor, it would support the hypothesis that creatine kinases play a role in the statin induced myopathy
Posted from my mobile device
Posted from my mobile device
07 Nov 2023, 19:10
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Bunuel
Mice treated with certain statins intended to decrease blood pressure also experienced drug-induced toxic myopathy, also known as muscular degeneration. Scientists hypothesize that this may have occurred because the statins cause an over-activation of creatine kinases, which are known to cause muscular degeneration.
Which of the following experiments would yield the most useful results for analyzing the scientists’ hypothesis?
A. Administering statins to mice with increased creatine kinase activity and observing creatine kinase activity.
B. Injecting mice with a creatine kinase inhibitor before administering the statins and then monitoring muscle tissue response.
C. Injecting mice with creatine kinase inhibitors and then monitoring muscle tissue response.
D. Injecting mice with muscle repair medication and then monitoring levels of muscular response.
E. Measuring mice’s level of muscular myopathy, administering a creatine kinase inhibitor, and then measuring myopathy once more
Which of the following experiments would yield the most useful results for analyzing the scientists’ hypothesis?
A. Administering statins to mice with increased creatine kinase activity and observing creatine kinase activity.
B. Injecting mice with a creatine kinase inhibitor before administering the statins and then monitoring muscle tissue response.
C. Injecting mice with creatine kinase inhibitors and then monitoring muscle tissue response.
D. Injecting mice with muscle repair medication and then monitoring levels of muscular response.
E. Measuring mice’s level of muscular myopathy, administering a creatine kinase inhibitor, and then measuring myopathy once more
OA is B.
Now we can easily understand by simple analogy, if doctor prescribes sometimes medication they also provide some Tablets that reduces the amount of acid produced in the stomach, why so? Because they think this medicine can produce acid and can form gas.
Just like here -> Doctor hypothesize that statins cause an over-activation of creatine kinases. How to resolve this?
Injecting mice with a creatine kinase inhibitor before administering the statins and then monitoring muscle tissue response.
If this resolves it we can definetly say,it is beacuse of this, issue has happened otherwise no.
Let us start with option elimination:
A. Administering statins to mice with increased creatine kinase activity and observing creatine kinase activity. -> This is wrong, it just means person is suffering from acidity and you giving medicine which will result in more acidity.
B. Injecting mice with a creatine kinase inhibitor before administering the statins and then monitoring muscle tissue response.
Exactly what we thought, Ans is this.
C. Injecting mice with creatine kinase inhibitors and then monitoring muscle tissue response. -> Even if we Inject mice with creatine kinase inhibitors, we don't know about is this statin responsible for this? so wrong.
D. Injecting mice with muscle repair medication and then monitoring levels of muscular response. -> Even if we do this, we don't know about is this statin responsible for this? so wrong.
E. Measuring mice’s level of muscular myopathy, administering a creatine kinase inhibitor, and then measuring myopathy once more-> Even if we do this, we don't know about is this statin responsible for this? so wrong.
