I''ve seen people do pretty well by doing as many questions as they can and then guessing on the last handful. That this would occur makes sense, since you can miss more than five questions and score rather high on quant, and OK on verbal.
At the same time, I have also gotten the sense that, if your score is more in question when you get to the last five questions, you can really drive it down. For instance, let's say that you were just managing to score V37 and had already missed some medium questions when you got to the last five questions and missed all of those last five. From what I have seen, you could end up scoring in the low 30s.
So, if you're going to guess, then guess on some of the hardest questions along the way, and maybe on one or two at the end of the section.