Researchers who conducted a one-year study found that one marijuana cigarette deposits four times more tar in smokers' lungs than does one tobacco cigarette. The researchers concluded that marijuana smokers are more likely to suffer from tar-induced lung cancer than are tobacco smokers.
Which of the following statements, if true, would most seriously weaken the researchers' conclusion described .above?
(A) The marijuana cigarettes used in the study were substantially smaller than the marijuana cigarettes smoked by the. typical user.
(B) None of the human participants in the study had ever smoked tobacco or marijuana in the past.
(C) A follow-up examination conducted five years after the original study showed that none of the human participants had tar-induced lung cancer.
(D) The tobacco cigarettes used in the study contained slightly more tar than the tobacco cigarettes smoked by the typical user.
(E) The typical user of marijuana smokes much less frequently than does the typical user of tobacco.