For those as challenged with math as myself, try this (apologies if this has already been done):
Consider the "slot method"
We need to select three people out a total of ten people (5 couples=10ppl), so create three "slots"
_ _ _
1 2 3
The only restrictions we have are that we cant pick an individual and that individual's spouse, nor can we select any individual twice. Knowing this, we can put any of our 10 people in the first slot. The second spot, however, will be limited to 8ppl (10 total less the person we placed in spot one, leaves 9, less that person's spouse, leaves 8). The third slot will only have 6 possibilities (10 total less the two ppl already placed and each of their spouses). Fill in the slots:
10 8 6 1 2 3
We would then multiply across to get 10*8*6=480
When using the Slot method, if the order of the selections does not matter (as is the case here) we must divide the the product of the slots by n!, where n is just the number of slots.
480/3! =480/6 = 80
Generally, you'd want to simplify before dividing, so the 2*3 in the 3! term would cancel the 6 in the numerator, and you'd just be left with (10*8)/1 or 80.