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Bunuel
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Bunuel,
How are we able to comprehend that the subjects and mice have similar functions, at least in terms of brain functioning?
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I did not quite understand the solution. Question - how are we supposed to draw the parallel between some chemical affecting mice and that chemical having the same effect in humans? It seems like a leap to arrive at this solution and the question does not hint at it.
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Hi!

My 2 cents on that:

I had a similar thought when solving this one, but after spending some time on it, I came to the conclusion that:

  1. Even though, as you mentioned, we can't definitively draw a parallel between mice and humans, there’s still a reasonable possibility that a chemical affecting mice could also influence humans. So ruling out that possibility can strengthen the argument by narrowing down Aldolase as the likely cause.
  2. The other four options clearly don't work, so even if (B) feels a bit of a stretch, it’s still the best available support for the conclusion.
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I did not quite understand the solution. Question - how are we supposed to draw the parallel between some chemical affecting mice and that chemical having the same effect in humans? It seems like a leap to arrive at this solution and the question does not hint at it.
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Bunuel
Aldolase is a protein found in the brain. In an experiment, human subjects who consistently chose sweetened drinks when offered a choice between salty and sweetened drinks were found to have significantly higher concentrations of aldolase in their brains than did subjects who consistently chose salty drinks over sweetened drinks. This observation strongly supports the conclusion that aldolase causes subjects to crave sweetened drinks.

Which one of the following, if true in human subjects, supports the argument the most?


A. The craving for sweetened drinks does not invariably result in choosing those drinks over salty drinks.
B. see below
C. The chemical components of aldolase are present in both sweetened and salty drinks.
D. Concentrations of aldolase detected in the brain are significantly higher after taking sweet beverages than those detected before.
E. Subjects that metabolize sugar less efficiently than do other subjects develop high concentrations of aldolase in their brains.

Aldolase is a biochemical, not a trademarked product, so it should not be capitalized.

.

Addition of "in human subjects" is essential to give the answer choices the tight relevance that they need for the GMAT. (The answer choice about mice should be purged—see below.)

.

Choice B (the current version in the OP) lacks the tightly circumscribed relevant specifics that it needs to be a correct answer. This choice is at least quadruple-irrelevant:

/1/ Humans are not mice. We can't just assume that mouse physiology extends to humans. (Most aspects of mouse physiology noted in medical experiments do NOT, in fact, extend to humans. The primary use of mouse studies is to provide a low-stakes sample on which to test toxicity, not from which to make observations and just blithely assume that those observations will extend to humans.)

/2/ No indication at all that the chemical mentioned in choice B is ever present in humans.

/3/ The chemical causes mice to crave sweet food. Sweet food ≠ sweet drinks.

/4/ What if there are 999 other brain chemicals involved in the same decision set? On top of the previously listed triple layers of irrelevancy, choice B also requires the presumption—without any evidence or related reasoning—that the 2 chemicals mentioned (one in the passage, one in choice B) are the only 2 brain chemicals that play any significant role in mice brains' navigation of these consumption decisions.

.

Since the basic argument in the passage contains a "correlation therefore causation" fallacy, we ought to rule out one of the two other potential ways to explain the correlation. In other words, to SUPPORT the assertion that "higher aldolase —> salty over sweetened drinks"—where the arrow represents causation—we could do either of the following:


i • DISMISS the possibility that "salty over sweetened drinks —> higher aldolase";


ii • NEGATE the possibilitiy of some third factor that causes BOTH the preference for the salty drinks AND the elevation of aldolase levels.

This correct answer performs function "i" above:


Repeated consumption of salty drinks does not decrease aldolase concentrations in the brain.

If repeated consumption of salty drinks DID decrease brain aldolase, then the correlation in the original passage would be explainable by reverse causation. This choice rules out that reverse causation, and can therefore be substituted for choice B as the new correct answer.

(Choice D, of course, is a wrong-way answer. I've written the new choice B in terms of salty drinks—which are the other half of the decision pair (besides sweet drinks)—so that choice D can be left as-is. (GMAC won't write two choices that are just directly contradictory opposite directions of the same type of statement. Had I written the new choice B as "Repeated consumption of sweet drinks does not raise brain aldolase levels", choice D would've had to go or be reworked.)
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