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Bunuel
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When we multiply out

(x + 1)(x - 2)(x + 3)(x - 4)...(x + 99)(x - 100)

we're multiplying 100 factors together, and to get terms with x^99 in them, we need to multiply the x's from 99 factors by the number in the one other factor. So if we multiply, for example, the "+1" in the first factor by the x's in the other 99, we get +x^99, then if we multiply the "-2" in the second factor by the x's in every other factor, we get -2x^99, and so on. So if we consider only the x^99 terms, we'll end up with 100 of them:

x^99 - 2x^99 + 3x^99 - 4x^99 + ....+ 99x^99 - 100x^99

and if we add these in pairs (add the first two, the second two, and so on) we get

-x^99 - x^99 - x^99 ... -x^99

and since we started with 100 terms that we grouped in pairs, we now have only 50 terms, so these sum to -50x^99, and the answer is -50.
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