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Unlike the opinion held by many of his peers that lasers were relatively simple, Arthur Ashkin adhered to his own more complicated ideas about how lasers might operate, and in 2018, at the age of 96, was awarded a Nobel Prize for his invention of 'optical tweezers'.

Solution:

A. Unlike the opinion held by many of his peers that lasers were relatively simple: Comparing Opinion to a person. Wrong.

B. Unlike the opinions of many of his peers that lasers were relatively simple: Comparing Opinion to a person. Wrong.

C. Compared to many of his peers’ opinions that lasers were relatively simple: Comparing Opinion to a person. Wrong.

D. Even though many of his peers were convinced that lasers were relatively simple: Correct

E. Even with many of his peers convinced of lasers being relatively simple: "With" tries to associate Arthur Ashkin with his peers. Does not make sense. We intend to show that even when his peers believed a certain idea, Arthur Ashkin stuck to his ideas. We need to show contrast. "with" tries to show accompaniment.
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