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In B, how does it weaken? B says it's possible the current drug has still more side effects, that is other than seizures. That logically makes the new drug preferable. So IMO B is ok. Although it isn't the OA.

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A new drug, taken twice daily for one month, is an effective treatment for a certain disease. The drug now most commonly prescribed for the disease occasionally has serious side effects such as seizures; the new drug has side effects much more frequently, but the worst of them is mild nausea. Therefore, the new drug is clearly preferable as a treatment.

Which of the following, if true, most seriously weakens the argument?

A) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it.
B) People who experience nausea are prone to discontinue use of the new drug prematurely.
C) Other drugs for the disease have typically been prescribed only for patients allergic to the most commonly prescribed drug.
D) People who have received effective treatment for disease do not generally contract the disease again.
E) There is a nonprescription medication that when taken with the new drug prevents the onset of nausea.


P.S.: there is a similar "complete the argument question" in GMAT Prep EP2:

https://gmatclub.com/forum/a-new-drug-taken-twice-daily-for-one-month-222505.html

A) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it. --> Conclusion is about new drugs. Not about current drug. Kind of Strengthener
B) People who experience nausea are prone to discontinue use of the new drug prematurely. --> If they are discontinue using prematurely, it may lead to other implications.
C) Other drugs for the disease have typically been prescribed only for patients allergic to the most commonly prescribed drug. : Other drugs, Out of context.
D) People who have received effective treatment for disease do not generally contract the disease again. --> Irrelevant, as it has nothing to related to the conclusion.
E) There is a nonprescription medication that when taken with the new drug prevents the onset of nausea. --> Strengthener. Hence, incorrect.
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Answer E is correct. The only side effect that the new drug produces is mild nausea. So if it is easy to eliminate this only side effect, you can conclude that the new drug is a better treatment.
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Which of the following most logically completes the argument?

A new drug, taken twice daily for one month, is an effective treatment for a certain disease. The drug now most commonly prescribed for the disease occasionally has serious side effects such as seizures; in field tests, the new drug’s side effects, though no worse than mild nausea, turned out to be much more frequent. Nevertheless, the new drug is clearly preferable as a treatment, since _____.

A) people who experience nausea are prone to discontinue use of the new drug prematurely
B) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it
C) other drugs for the disease have typically been prescribed only for patients allergic to the most commonly prescribed drug
D) people who have received effective treatment for disease do not generally contract the disease again
E) there is a nonprescription medication that when taken with the new drug prevents the onset of nausea


Moderator Note: Similar Question

Premise : A new drug, taken twice daily for one month, is an effective treatment for a certain disease.
The drug now most commonly prescribed for the disease occasionally has serious side effects such as seizures; in field tests, the new drug’s side effects, though no worse than mild nausea, turned out to be much more frequent.

Conclusion : Nevertheless, the new drug is clearly preferable as a treatment, since...(premise)

Pre-thinking : 1. May be there is no other drug available to cure the disease completely and this drug is highly effective.
2. There may be some medicine available to cure the nausea even while using this new drug.

Options :
A) people who experience nausea are prone to discontinue use of the new drug prematurely
If people stop using drug on experiencing nausea, this drug will not be preferable since the cases of nausea turned out to be frequent and more than expected.

B) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it
Current most commonly prescribed drug may also have side effects, but it has not been proven yet in the field tests while the new drugs side effect has been proved in the field test.

C) other drugs for the disease have typically been prescribed only for patients allergic to the most commonly prescribed drug
This is strengthening the use of most prescribed drug and not the new drug.

D) people who have received effective treatment for disease do not generally contract the disease again
Out of scope as it is talking about effective treatment and not about new drug.

E) there is a nonprescription medication that when taken with the new drug prevents the onset of nausea
Oh so there is a medication available that can prevent nausea while using the new drug. Fantastic. So this solves the problem.
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NandishSS
Which of the following most logically completes the argument?

A new drug, taken twice daily for one month, is an effective treatment for a certain disease. The drug now most commonly prescribed for the disease occasionally has serious side effects such as seizures; in field tests, the new drug’s side effects, though no worse than mild nausea, turned out to be much more frequent. Nevertheless, the new drug is clearly preferable as a treatment, since _____.

A) people who experience nausea are prone to discontinue use of the new drug prematurely
B) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it
C) other drugs for the disease have typically been prescribed only for patients allergic to the most commonly prescribed drug
D) people who have received effective treatment for disease do not generally contract the disease again
E) there is a nonprescription medication that when taken with the new drug prevents the onset of nausea


Moderator Note: Similar Question

GMATNinja DmitryFarber VeritasKarishma Why B is wrong? Is the "not yet been attributed to it" part? I mean, since the side effects are not attributed YET, we can evaluate between the new drug VS the commonly prescribed? Tks! :)
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Will2020 The trick here is that we want an answer that helps us compare the new drug favorably to the old one. We already know that the old drug has serious side effects. The only objection to the new drug is that its side effects may be more frequent. So ideally we'd strengthen the argument by finding one of three things: 1) a new reason to object to the old drug, 2) an additional advantage of the new drug, or 3) a reason not to worry about the new drug's side effects. E gives us option 3, so it's a solid strengthen.

B may seem to give us option 1, but does it really? Since we know that the old drug has bad side effects, it's not immediately helpful to learn that it MAY have additional side effects, without any mention of their frequency or severity. Sure, any side effects could be considered bad (unless they are "leads to perfect verbal scores" or something like that), but any drug MAY have unknown side effects. For all we know, the same is true of the new drug! Also, since we don't know the severity of these side effects, we don't know how to compare them to the known side effects of the new drug. So while B seems to point in the right general direction (something bad about the old drug), it doesn't give us enough clarity to make a different decision than we would already have made. Contrast that to E, which allows us to clearly conclude that the worst side effect of the new drug can be neutralized, making it clearly preferable to the more dangerous old one.
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AndrewN, I would love your take on this question, I narrowed it down to B,D and E, eliminated E, spent some time dilly dallying over B and D and finally chose D and turns out I am wrong.
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AndrewN, I would love your take on this question, I narrowed it down to B,D and E, eliminated E, spent some time dilly dallying over B and D and finally chose D and turns out I am wrong.
Hello, kntombat. The goal here is to most logically address why a new drug, despite certain side effects that were much more frequent than those of a drug currently prescribed, would be clearly preferable. I do not prefer to pre-think possibilities when answers are there for me to lean on, so I will jump right in.

NandishSS
Which of the following most logically completes the argument?

A new drug, taken twice daily for one month, is an effective treatment for a certain disease. The drug now most commonly prescribed for the disease occasionally has serious side effects such as seizures; in field tests, the new drug’s side effects, though no worse than mild nausea, turned out to be much more frequent. Nevertheless, the new drug is clearly preferable as a treatment, since _____.

A) people who experience nausea are prone to discontinue use of the new drug prematurely
I spent the longest on this answer, believe it or not, perhaps because it was the first one, and my mind needed to warm up to the task. (Even so, I spent just over a minute and a half on the question altogether, so I was not upset with myself or anything.) But if people would more likely stop using the new drug to treat this ailment, then we would have a compelling reason to stick with the old treatment instead. This is the opposite of what we want. Red light.

Quote:
B) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it
This is similar to a some answer. It is possible, really? Then it is just as likely that anything that follows the first that above is not true of the drug now most commonly prescribed. We have no context to lean on in the passage for guidance. We cannot (or should not) rely on hearsay, more or less, to buttress this argument. Red light.

Quote:
C) other drugs for the disease have typically been prescribed only for patients allergic to the most commonly prescribed drug
So what? We are not interested in other drugs, only in the new one versus the currently prescribed one. We cannot comment on the efficacy of these other drugs, and we cannot create any meaningful link between this information and the new drug under consideration. Red light.

Quote:
D) people who have received effective treatment for disease do not generally contract the disease again
This applies equally to the old drug and the new drug. We are not addressing the real issue here, why the new drug would be clearly preferable. Be careful not to be misled by blanket statements. If the passage provided information on how long each treatment took, and the one currently in use took much longer, then yes, perhaps the new drug would be preferable, but the passage says nothing to this effect. Red light.

Quote:
E) there is a nonprescription medication that when taken with the new drug prevents the onset of nausea
Not only does this medication combat the drawback of the new drug, it is also easy to obtain, since a prescription is not even required. This information definitely tilts the balance in favor of the new drug, just what we want. Green light.

I hope that helps. Thank you for thinking to ask me about this one.

- Andrew
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AndrewN

Quote:
B) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it
This is similar to a some answer. It is possible, really? Then it is just as likely that anything that follows the first that above is not true of the drug now most commonly prescribed. We have no context to lean on in the passage for guidance. We cannot (or should not) rely on hearsay, more or less, to buttress this argument. Red light.

I hope that helps. Thank you for thinking to ask me about this one.

- Andrew

Hi AndrewN- was wondering if you think this is another weakeness in B

In B -- We dont know if the un-attributed side effect (for the drug now most commonly prescribed) is something that patients will bother about ?

For example -
- if the patients are aneroxic patients.
- if the un-attributed side effect (for the drug now most commonly prescribed) turns out to be weight gain

Perhaps aneroxic patients are NOT really bothered by this new / un-attributed side effect ?

Given we dont know if the patients eventually would be bothered / would not be bothered ONCE un-attributed side effect (for the drug now most commonly prescribed) is found == we can eliminate B

Thoughts ?
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AndrewN

Quote:
B) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it
This is similar to a some answer. It is possible, really? Then it is just as likely that anything that follows the first that above is not true of the drug now most commonly prescribed. We have no context to lean on in the passage for guidance. We cannot (or should not) rely on hearsay, more or less, to buttress this argument. Red light.

I hope that helps. Thank you for thinking to ask me about this one.

- Andrew

Hi AndrewN- was wondering if you think this is another weakeness in B

In B -- We dont know if the un-attributed side effect (for the drug now most commonly prescribed) is something that patients will bother about ?

For example -
- if the patients are aneroxic patients.
- if the un-attributed side effect (for the drug now most commonly prescribed) turns out to be weight gain

Perhaps aneroxic patients are NOT really bothered by this new / un-attributed side effect ?

Given we dont know if the patients eventually would be bothered / would not be bothered ONCE un-attributed side effect (for the drug now most commonly prescribed) is found == we can eliminate B

Thoughts ?
Hello, jabhatta2. I think you may be confusing preferable from the final line of the passage (for reference, the new drug is clearly preferable as a treatment) as a preference that a disease sufferer might have. The argument is put forth by some unknown or unidentified person or group as a general truth. This person is speaking without sufferers in mind, but with an eye on side effects, those known to occur with the use of the old drug versus those experienced with the use of the new drug. As such, I do not think we can eliminate answer choice (B) based on whether sufferers of this disease would be bothered by certain side effects. Such a consideration goes beyond what I deem fitting for CR logic, which tends to be more straight-arrow: the new drug has a certain side effect that occurs more frequently, but that side effect can readily be mitigated (by a nonprescription medication).

By the way, I am not sure that your real-world scenario is apt. I am not saying that every anorexic is the same, but I have known one in my life, and this person would never see weight gain as a positive. Many anorexics starve themselves not only because they think they look or feel better, but because they enjoy the attention that people show them because of their gaunt appearance, even thriving from a hospital stay. It is a mental disease as well as a physical one. It is quite difficult to change an entrenched belief, even after physical symptoms of dysfunction start to manifest.

I see what you were driving at, but I think your associative reasoning took over. You do not need to craft a little story to find a weakness. Just look for the easiest target, eliminate if possible, and move on.

Thank you for following up.

- Andrew
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Hi avigutman - what do you think of these options

Quote:

(Option F) The new drug is commonly used by celebrities as the new drug helps to stop the aging process.

Do you think an answer like this WOULD BE apt ?

I think no because we need to look for answer choices within the context of "the new drug is clearly preferable as a treatment"

Quote:

(Option G) The old drug DEFINITELY has side effects related to 'increasing the aging process'

Do you think an answer like this WOULD BE apt ?

I think no because we need to look for answer choices within the context of "the new drug is clearly preferable as a treatment"

Quote:

(Option H) The old drug's side effects such as seizures can be just as frequent as the new drug's side effects

I think this WOULD be an answer.
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Hi avigutman - what do you think of these options

Quote:

(Option F) The new drug is commonly used by celebrities as the new drug helps to stop the aging process.

Do you think an answer like this WOULD BE apt ?

I think no because we need to look for answer choices within the context of "the new drug is clearly preferable as a treatment"

Quote:

(Option G) The old drug DEFINITELY has side effects related to 'increasing the aging process'

Do you think an answer like this WOULD BE apt ?

I think no because we need to look for answer choices within the context of "the new drug is clearly preferable as a treatment"

Quote:

(Option H) The old drug's side effects such as seizures can be just as frequent as the new drug's side effects

I think this WOULD be an answer.
jabhatta2 We don't have information comparing the effectiveness of the two drugs, but we do have information comparing the side effects of the two drugs. We know that the old drug has worse side effects at a low frequency, and the new drug has more mild side effects at a higher frequency.
The author claims that the new drug is preferable, but the justification for that claim is missing.
I don't know that I'm able to categorically say that frequent mild side effects are preferable to infrequent severe side effects. Can you?
That's why the author needs answer choice (E). We're looking for an answer choice that makes it EASY to identify which of the above highlights is preferable. (F) and (G) give a point to the new drug, but they don't justify the author's use of the word "clearly" (i.e. it's still not OBVIOUS that frequent mild side effects + stopping the aging process is preferable to infrequent severe side effects + increasing the aging process). Would you be willing to vomit every 10 minutes of your life if it means that you don't age? I doubt it.
Answer (H) goes against one of the premises of the argument:
Quote:
the new drug’s side effects, though no worse than mild nausea, turned out to be much more frequent
If (H) were true, then yes, that would work. It's OBVIOUS that mild side effects are preferable to severe side effects, all else (namely, the frequency) being equal.
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Hi experts KarishmaB MartyMurray DmitryFarber

(D) people who have received effective treatment for disease do not generally contract the disease again

I don't understand how (D) is not correct here. Is it wrong because (D) doesn't clearly highlight the advantage of the new drug over old drug?
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Hi agrasan,

I’m happy to help. Yes you’re correct in that there’s no advantage of the new drug over the current drug. The current drug, one would assume, is also effective as it’s the recommended course of treatment.

Hope this helps. Let me know if anything is unclear.


agrasan
Hi experts KarishmaB MartyMurray DmitryFarber

(D) people who have received effective treatment for disease do not generally contract the disease again

I don't understand how (D) is not correct here. Is it wrong because (D) doesn't clearly highlight the advantage of the new drug over old drug?
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Which of the following most logically completes the argument?

A new drug, taken twice daily for one month, is an effective treatment for a certain disease. The drug now most commonly prescribed for the disease occasionally has serious side effects such as seizures; in field tests, the new drug’s side effects, though no worse than mild nausea, turned out to be much more frequent. Nevertheless, the new drug is clearly preferable as a treatment, since _____.


This is a Complete the Passage question. So, the correct answer must logically complete the passage in a way that takes into account all relevant parts of the passage.

Reading the passage we see the following key aspects.

The blank is preceded by the support marker "since." That indicates that the choice that fills the blank must support what precedes "since," which is the following:

Nevertheless, the new drug is clearly preferable as a treatment

Also, looking above in the passage, we see that the new drug is being compared with "the drug now most commonly prescribed for the disease" and that the following is true.

the new drug’s side effects, though no worse than mild nausea, turned out to be much more frequent

So, the correct answer must do the following: provide a reason why the new drug is "preferable" to "the drug now most commonly prescribed for the disease" even though the new drug's side effects are "more frequent."

Now that we are clear regarding what the correct answer must do, we can go to the answer choices.

A) people who experience nausea are prone to discontinue use of the new drug prematurely

The passage seems to suggest that the new drug causes mild nausea relatively frequently.

So, if anything, this choice indicates a reason why the new drug is not preferable.

After all, if the new drug causes mild nausea and people who experience nausea are prone to discontinue use of the new drug prematurely, then it could be that, relatively frequently, treatment with the new drug won't have the desired outcome.

Eliminate.

B) It is possible that the drug now most commonly prescribed has side effects that have not yet been attributed to it

The fact that the most commonly prescribed drug may have unknown side effects is not a reason to prefer the new drug.

After all, something that is possible is but not currently believed to be the case is not a clear reason to prefer the drug.

Eliminate.

C) other drugs for the disease have typically been prescribed only for patients allergic to the most commonly prescribed drug

This choice seems to indicate that, in general, drugs other than "the most commonly prescribed drug" are rarely prescribed.

The fact that other drugs are not preferred over the most commonly used one is not a reason to prefer the new one over the most commonly used one.

Eliminate.

D) people who have received effective treatment for disease do not generally contract the disease again

The passage says that the new drug is "effective." So, this choice could seem to provide a reason why the new drug would be preferred.

At the same time, this choice doesn't actually work since it doesn't provide a basis for comparison with "the most commonly prescribed drug."

After all, presumably, or at least for all we know, the most commonly prescribed drug is also effective.

Even if the most commonly prescribed drug not effective, this choice doesn't say so. All this choice does is present the outcome of effective treatment.

In short, this choice doesn't provide a clear reason to prefer the new drug over the most commonly prescribed one because it doesn't provide new information about either drug.

Eliminate.

E) there is a nonprescription medication that when taken with the new drug prevents the onset of nausea

This choice is interesting.

The passage says that the side effects of the new drug are "no worse than mild nausea." So, mild nausea, which is "mild" already, is the worst side effect of the new drug.

Now, this choice indicates that even that side effect can be avoided through taking of a medication, which presumably is relatively benign since it's "nonprescription."

Thus, we can see that this choice indicates why the new drug is preferable even though its side effects are more frequent by indicating that worst of those side effects is preventable through use of a likely relatively benign medication.

Keep.

Correct answer: E
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agrasan
Hi experts KarishmaB MartyMurray DmitryFarber

(D) people who have received effective treatment for disease do not generally contract the disease again

I don't understand how (D) is not correct here. Is it wrong because (D) doesn't clearly highlight the advantage of the new drug over old drug?
Focus on the last sentence:
the new drug is clearly preferable as a treatment, since _____.

We need something that tells us why the new drug is preferable.

Option (D) is quite irrelevant. Nothing in the argument says that the current drug is not effective. It is being commonly prescribed so it must be effective. The whole story is of side effects. Old drug has occasional but serious, new drug has mild but more frequent. So what is better? Option (E) tells us that new drug side effects are avoidable. Then new drug certainly becomes better.
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