I'm applying for HBS 2+2 in late 2011.
Stats in detail (hope this helps other 2+2's):
3.1 GPA undergrad/3.5 GPA last two years. State school.
Economics major, marketing minor
GMAT 680-720 on practice exams
Recommendations from HBS grad and VP of large Aerospace company
Director of fundraising for entrepreneur club - raised over $10k individually to send the entire club to Chicago for national business plan competition
First person in my family to make it to college
Worked 20-65 hrs weekly throughout college (paid my way through)
Latin/Hispanic female
Owned 4 profitable dance studios, sold them
Worked internship in Aerospace/Defense for 2 years (part-time)
Volunteer work: creating start-ups with high school entrepreneurs.
I have consistent focus on start-ups and work experience, but not so much on academics. Not sure how disadvantaged I am, but I am looking forward to applying. I'm even looking forward to the application process--it should help me discover myself and reveal my motivations.