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The premise states that some people accept gene replacement therapy if it is used for medical treatment, but not if it used for performance enhancement. Now, in the conclusion new information is presented: regulations that will be formulated regarding gene replacement, which need a clear distinction between medical treatment and performance enhancement. So what could be a possible answer? An answer choice that deals with the new information in the conclusion: the regulations. IMPORTANT: we are filling a blank not for the main conclusion but an intermediary conclusion, creating a causal relationship with the main conclusion. Choice A is the only choice that mentions or takes position on regulations, hence it is the correct choice. B is out of scope and nothing in the argument could actually explain such a causal relationship. So is C, it is rather a statement that would need an additional assumption. D is incorrect as it presents a stated assumption that is not connected to the main conclusion in any way. To arrive at E one needs an additional assumption that is unstated here, that if those distinctions are not clearly formulated, gene replacement therapy will cease to exist and that will lead to not realizing the potential of it. This is not allowed in filling the blank arguments. We need to finish the thought that logically follows the information provided.
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MartyMurray AjiteshArun GMATNinja
my reason for E was because regulations are not to merely reflect sentiments of people (Just because I don't like something or feel comfortable with - is not true purpose of execution of regulation) but also be of value/cause change/benefit of people
So the thought behind E is as one level beyond the merely reflecting sentiments that if this distinction is not made, then gene replacement will not be used even for disease as people will protest it for performance improvement...which is why benefits won't be realized.
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MartyMurray AjiteshArun GMATNinja
my reason for E was because regulations are not to merely reflect sentiments of people (Just because I don't like something or feel comfortable with - is not true purpose of execution of regulation) but also be of value/cause change/benefit of people
So the thought behind E is as one level beyond the merely reflecting sentiments that if this distinction is not made, then gene replacement will not be used even for disease as people will protest it for performance improvement...which is why benefits won't be realized.
Hi MalachiKeti,

Let's take a look at the statement that we get with option E:

"A clear distinction should therefore be made between medical treatment and performance enhancement when regulations concerning gene replacement are being formulated, because otherwise the potential benefits of gene replacement will never be fully realized."

The word otherwise means we need something that will happen if we don't do the first thing mentioned ("a clear distinction should therefore be made"). Now, if we don't make a clear distinction between medical treatment and performance enhancement when formulating the regulations, can we say that the potential benefits of gene replacement will never be fully realized­? Remember to weigh both A and E, and then mark the one that looks like a better fit given the information in the stimulus.
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