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Rashed12
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Rashed12
Once Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he had hoped.


A. Once Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he had hoped.
B. Once Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he hoped.
C. As Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he had hoped.
D.Once Dr. Benner and his colleagues combined real atoms, according to his designs, he had hoped and the artificial bases didn’t work.
E. When Dr. Benner and his colleagues combined real atoms at any time, according to his designs, he had hoped and the artificial bases didn’t work.



IMO A!
I focused on meaning as taught in a webinar by egmat.
Also it uses the correct tense and includes the word “Had”
A friend of mine gave me this amazing tip he said “whenever one action is done before another one in the past we use “had”

B omits “had” which kinda changes the meaning

C “As Dr. Benner and his colleagues combined..”
the word AS changes the meaning and (correct me if I am wrong) it suggests that action A (combined real atoms) and action B (bases didn’t act as he had hoped) happened at the same time.

D
“he had hoped and the artificial bases didn’t work.“
Again meaning changed and makes the sentence a bit awkward


E
Same as D
The start “when” is also wrong


Experts please correct my approach. Other than that I hope this helped

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Rashed12
Once Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he had hoped.


A. Once Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he had hoped.
B. Once Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he hoped.
C. As Dr. Benner and his colleagues combined real atoms, according to his designs, the artificial bases didn’t work as he had hoped.
D.Once Dr. Benner and his colleagues combined real atoms, according to his designs, he had hoped and the artificial bases didn’t work.
E. When Dr. Benner and his colleagues combined real atoms at any time, according to his designs, he had hoped and the artificial bases didn’t work.

Meaning: the bases didn't work as he HAD hoped, once he and the others combined real atoms.
Rule: Past Perfect Tense or "had" is used to describe an event in the past before another event in the past.
Here, we need "had" as the correct tense, because the Dr. "hoped" before he "combined the atoms", and both of these happened sequentially in the past.

(B) missing "had".
(C) "as" in this context can be used to indicate that something happens during the time when something is taking place, or it can be used to say "because" or "since"; both cases distorts the intended meaning: the bases didn't work because they combined the atoms, we can't infer that, maybe it was something else; also, the bases didn't work while they combined the atoms, they didn't work after or "once" they combined the atoms.
(D) "combined real atoms…he had hoped and the artificial bases didn’t work" this is not parallel and unintended.
(E) "combined real atoms…he had hoped and the artificial bases didn’t work" this is not parallel and unintended; also, "when" is used to express at or during the time that, which in this is unintended;

Answer (A).
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