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Cool reasoning. I agree - the sample should be specific. I was concentrating on the word "general" in E - that is a spoiler. Because the author's conclusion is definitely based on "regional" population. The regional sample should represent the genetic dispositions.

Infact another way to look at A is - X->Y (x leads to y) scenario. NO OTHER factor other than X leads to Y. A is the same ! A bolster the claim.
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I also picked A. I discarded E because you only need to prove that much of the variation in the incidence of THE MENTIONED ailments is due to genetic makeup. So, we don't need to enlarge the ailments pool to strengthen the argument. A says exactly what we need, while E tries to enlarge the pool but does not bring any evidence that would support the author's claim. If the mentioned ailments were representative to even all the existent ailments, we wouldn't still be able to prove whether the author's observation proceeds.

Ahh.. yes. So what if the ailments were representative.. We need to prove that genetic factors are responsible for those ailments. E doesn't do that at all and thats why its wrong.

Good explanation. Thanks..
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