Discovered in Cambodia in 2015, Cassava Mosaic Disease
spread to Thailand and Vietnam by 2018 and was now estimated to be present in 10 percent of the surfaces cultivated in the region threatening millions of smallholders that cultivate cassava and generates US$4 billion in export revenue
A. spread to Thailand and Vietnam by 2018 and
was now estimated to be present in 10 percent of the surfaces cultivated in the region threatening millions of smallholders that cultivate cassava and
generates -- Estimation is being done in present, so "is now estimated" is correctB. had spread to Thailand and Vietnam by 2018 and is now estimated to be present in 10 percent of the surfaces cultivated in the region, threatening millions of smallholders who cultivate cassava and generate
-- CORRECT, "by 2018" indicator makes past participle correct and right usage of participial modifier phrase (threatening...)C.
spreading to Thailand and Vietnam by 2018 and
is now estimated to be present in 10 percent of the surfaces cultivated in the region threatening millions of smallholders cultivating cassava and generating
-- wrong parallelismD. had spread to Thailand and Vietnam by 2018 and
had been estimated to be present in 10 percent of the surfaces cultivated in the region, threatening millions of smallholders who cultivate cassava and generate
-- same reason as AE.
has spread to Thailand and Vietnam by 2018 and is now estimated to be present in 10 percent of the surfaces cultivated in the region, threatening millions of smallholders who cultivate cassava and
generates [/color[color=#ff0000]]-- The situation ended in past (2018), so present perfect tense is wrong; also has SVA issue.So,
B