Bunuel
12 Days of Christmas GMAT Competition with Lots of FunDigoxin, used for millennia to treat heart disease, is a chemical
that derives from the common foxglove, a flowering plant native to most of Europe, and that was first isolated by English researcher Dr. Sydney Smith.
(A) that derives from the common foxglove, a flowering plant native to most of Europe, and that was first isolated by English researcher Dr. Sydney Smith
(B) that had derived from the common foxglove, a flowering plant native to most of Europe, and first been isolated by English researcher Dr. Sydney Smith
(C) derived from the common foxglove, a flowering plant native to most of Europe, and that was first isolated by English researcher Dr. Sydney Smith
(D) that was first isolated by English researcher Dr. Sydney Smith and then derives from the common foxglove, a flowering plant native to most of Europe
(E) first isolated by English researcher Dr. Sydney Smith and that derived from the common foxglove, a flowering plant native to most of Europe

Manhattan Prep Official ExplanationFirst Glance: Differences in the answer choices provide clues about what a problem might be testing. Before reading the sentence, glance at the beginning of the underline and down the beginning (just the beginning!) of the five answer choices to look for one early clue as to what this sentence is testing. In this sentence, some choices begin with the word that and some drop the word
that; there may be sentence structure issues going on. Also, the verb tense changes (
derives, had derived, derived), so pay attention to the meaning to figure out what verb tense makes sense.
Issues:(1) Parallelism: X and Y structure
The first
that is part of a broader parallel structure:
a chemical that X and that Y.
(A) that derives from … and that was first isolated by …
(B) that had derived … and first been isolated by …
(C) derived from … and that was first isolated by …
(D) that was first isolated by … and then derives from …
(E) first isolated by … and that derived from …
It’s fine to have
that in front of both X and Y or to have it only in front of X. However, it’s not okay to have the word
that only at the beginning of the Y (second) element but not at the beginning of the X (first) element, so eliminate choices (C) and (E).
Correct:
that X and that YCorrect:
that X and YIncorrect:
X and that YNext, check the rest of the parallel structure for the remaining choices. In all three, the two elements both start with verbs, so that’s good.
(2) Verb TenseWhile choice (B) does use a parallel structure, the verbs are
had derived and (
had) been isolated (the
had has to carry over to the second verb because
been isolated, by itself, is not a complete verb form). These verbs are in past perfect form, which is used when you want to talk about the first of two events that happened at different times in the past. In this sentence, there is no second past event that took place later in time—a requirement when using past perfect. The only other verb (
digoxin … is) is in the present tense. Eliminate (B) for using past perfect incorrectly.
(3) MeaningAnswer (D) has a logic problem. It says that
digoxin … was first isolated by someone and
then derives (comes)
from … foxglove. It doesn’t make sense to say a specific researcher
first isolated digoxin and only then did the chemical come from the plant. The chemical was already present in the plant. Then the researcher figured out how to extract/isolate it. Eliminate answer (D) for an illogical meaning.
The Correct Answer: Answer (A) employs a correct parallel structure:
that derives from … and that was first isolated. It’s acceptable for two parallel verbs to be in different tenses, as long as those tenses make sense in the context of the sentence. In this case, it’s still true that the chemical
derives from foxglove, so that fact should be stated in present tense.