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Pancreas releases enzymes that control the amount of sugar in blood. An endocrinologist observed that subjects with low-functioning pancreas usually have poorer cardiac health than do people with average to high levels of pancreatic function. Thus, the endocrinologist concluded that high pancreatic function is vital for maintaining blood sugar level as well as cardiac health.

The endocrinologist’s conclusion depends on which of the following assumptions?

A) High pancreatic function ensures good cardiac health better than normal pancreatic function does.
B) Irregular blood sugar is similar to poor cardiac health in its physiological effects.
C) Those whose bodies maintain high pancreatic function cannot develop poor cardiac health.
D) Treating irregular blood sugar with insulin is not as effective as treating poor cardiac health with cardiac therapy.
E) Poor cardiac health does not result in a decrease in pancreatic function.



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Assumption question:

Using pre-thinking approach to skim through the options:

Under what condition high pancreatic function is not vital for maintaining blood sugar level as well as cardiac health.
Given that
Pancreas releases enzymes that control the amount of sugar in blood.
A low-functioning pancreas usually have poorer cardiac health than do people with average to high levels of pancreatic function.

Case1:
What if poor cardiac health leads to low functioning pancreas in that case its the opposite way round and breaks the conclusion.
So.
Assumption1: Poor cardiac health does not leads to low functioning pancreas.
With this in mind lets go through the options:

A) High pancreatic function ensures good cardiac health better than normal pancreatic function does.
Irrelevant.

B) Irregular blood sugar is similar to poor cardiac health in its physiological effects.
It's not about how much similar they are but whether one leads to another.

C) Those whose bodies maintain high pancreatic function cannot develop poor cardiac health.
Research states that usually the people with high pancreatic function do not face cardiac issue. This is too extreme to be true.

D) Treating irregular blood sugar with insulin is not as effective as treating poor cardiac health with cardiac therapy.
Irrelevant.

E) Poor cardiac health does not result in a decrease in pancreatic function.
Exactly in line with our pre-thinking approach.
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A) High pancreatic function ensures good cardiac health better than normal pancreatic function does.

Out of scope as the passage concludes high pancreatic function is vital for maintaining blood sugar level as well as cardiac health. We are not given any information about the comparison of high pancreatic function and normal pancreatic function.

B) Irregular blood sugar is similar to poor cardiac health in its physiological effects.

Distortion

C) Those whose bodies maintain high pancreatic function cannot develop poor cardiac health.

'cannot develop' is extreme. We are not concluding that high pancreatic function cannot develop poor cardiac health

D) Treating irregular blood sugar with insulin is not as effective as treating poor cardiac health with cardiac therapy.

Out of scope, alternative plan.

E) Poor cardiac health does not result in a decrease in pancreatic function.

If poor cardiac heath is a result of decrease pancreatic function, then the conclusion falls apart.
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Question Stem

Pancreas releases enzymes that control the amount of sugar in blood. An endocrinologist observed that subjects with low-functioning pancreas usually have poorer cardiac health than do people with average to high levels of pancreatic function. Thus, the endocrinologist concluded that high pancreatic function is vital for maintaining blood sugar level as well as cardiac health.

The endocrinologist’s conclusion depends on which of the following assumptions?

Breakdown

Premise 1: The pancreas controls blood sugar

Premise 2: Low-functioning pancreas usually have poorer cardiac health than normal-functioning pancreas.

Conclusion: The high-functioning pancreas leads to stable blood sugar and good cardiac health.

Gap: There is a directionality in the cause-effect. High functioning LEADS to stable blood sugar and cardiac health.

Evaluating the answer choices

A) High pancreatic function ensures good cardiac health better than normal pancreatic function does.

We are not comparing the high-functioning with the normal-functioning pancreas. Rather, the argument here is a high-functioning pancreas is required for good cardiac health. Thus, Out-of-scope

B) Irregular blood sugar is similar to poor cardiac health in its physiological effects.

Let's negate. The physiological effects of irregular blood sugar and poor cardiac health are different. Does this break the conclusion? No. It may help doctors to decipher that you have one or the other but the underlying reason for the effect may be a low-functioning pancreas.

C) Those whose bodies maintain high pancreatic function cannot develop poor cardiac health.

This choice is extreme to me. There may be other vital bodily functions that might lead to poor cardiac health if they aren't performing normally. For example, you may have a high functioning pancreas but if you are not that physically active then you may have poor cardiac health.

D) Treating irregular blood sugar with insulin is not as effective as treating poor cardiac health with cardiac therapy.

Treatment like insulin and cardiac therapy may effect the blood sugar and cardiac health but it does not change the argument. Thus, it is out of scope.

E) Poor cardiac health does not result in a decrease in pancreatic function.

This reinforces the directionality of cause-effect we spoke of before. Let's negate it. Poor cardiac health results in a decrease in pancreatic functioning. If this were true, then the argument ceases to make sense.

Thus, the correct answer choice is E.
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