In 1955 the president of the World Health Organization (WHO) announced at the World Health Summit that the WHO was initiating an international effort to rid the world of malaria. With international funding and cooperation, he argued, and with the use of newly developed medicines such as chloroquine and powerful new insecticides like DDT, the world could finally rid itself of this terrible scourge.
The WHO malaria initiative was typical of the bold international initiatives of the postwar era. Idealists believed that the new model of intergovernmental bodies typified by the United Nations would usher in a new age of international cooperation, and that the striking technological advances of the age would solve all human ills. Indeed, the malaria effort was simultaneous with the global fight against smallpox, which would in fact eliminate this dreaded disease little more than two decades later.
Malaria, unfortunately, has been less amenable to eradication. No reliable vaccine has ever been developed against malaria, and consequently no area can ever be declared completely free of the disease as long as there is a single Anopheles mosquito in the area with the Plasmodium parasite in its gut. If the mosquito bites a human and transfers Plasmodium, the cycle starts all over again. Efforts to eradicate the mosquito showed some success in wealthy countries with temperate climates, such as Italy or Singapore, but in a poor, tropical country like India the Anopheles populations surged as soon as the WHO workers left. The wonderful new insecticides of the modern age turned out to be less wonderful than the idealists had hoped; DDT is great at killing mosquitoes, but it has lasting and widespread consequences for the environment and the health of local populations. Furthermore, doctors in the 1970s began to see disturbing signs that the Plasmodium parasite was developing resistance to quinine and other anti-malarial medicines as quickly as scientists were developing new medicines.
By 1978 the evidence was clear—the malaria eradication effort had failed. The WHO shifted its goal from eradicating malaria to controlling it. These efforts at control have seen only limited success. Today, over forty percent of the world’s population lives in areas exposed to malaria, and there are between 300 million and 500 million infections of the disease each year. The annual death rate due to malaria is higher now than it was a century ago.
1. The passage implies which of the following about future disease eradication programs?A. Intergovernmental organizations should not be too confident about the long-term effectiveness of any technology in their disease eradication programs.
B. All disease eradication programs run by intergovernmental bodies are doomed to failure.
C. Disease eradication programs can only be successful against relatively mild diseases, such as smallpox.
D. Eradication programs focusing on diseases carried by mosquitoes cannot be successful.
E. The greatest chance for success of disease eradication programs lies in the field of biotechnology, which will open up entirely new avenues for fighting disease.
2. The relationship of the Anopheles mosquito, the Plasmodium parasite, and the disease malaria is most similar to which of the following?A. Norwegian rats carry fleas that hold in their guts the Yersinia pestis bacteria, which can cause the bubonic plague in infected humans.
B. British army officers give Native Americans blankets infected with the Variola virus, which causes smallpox.
C. Tsetse flies that bite humans can transfer the Trypanosoma parasite, which in humans causes African trypanosomiasis, also known as sleeping sickness.
D. Parasitic Schistosoma flatworms breed in snails, which then excrete the flatworms into waterways where the flatworms can embed themselves in humans and cause schistosomiasis, also known as bilharzia or elephantiasis.
E. Cows consuming the remains of other cows with mutated prion proteins can develop bovine spongiform encephalopathy, also known as mad cow disease, which can be transferred to humans who eat tainted products from these cows.
3. Which of the following would be most representative of the “bold international programs” described in the second paragraph?A. The Soviet Union demands that its allied nations in Eastern Europe employ a new and advanced type of nuclear reactor in new power generating facilities.
B. Canada experiences a bumper wheat crop because of advances in agronomy, and it distributes its excess wheat to three nations in subSaharan Africa that are suffering from drought.
C. A consortium of nations in South Asia cooperates in the construction of a new type of desalinization plant that will supply water to all member nations.
D. Teams of French and Italian scientists sponsored by their respective governments race to be the first to develop an effective vaccine against cholera.
E. Eight national chess organizations from different nations agree to join together into an international chess organization that will work for the standardization and promotion of the game.
4. Which of the following would most likely describe the reaction of the author of the passage to a call for a new international malaria eradication program?A. Enthusiastic support
B. Angry contempt
C. Amused ambivalence
D. Reluctant condemnation
E. Pessimistic support
5. The passage implies that which of the following would be most important to a successful eradication campaign against malaria?A. A new anti-malarial medicine
B. An effective vaccine against malaria
C. A stronger variant of DDT
D. Anopheles mosquitoes engineered to reject the Plasmodium parasite
E. Greater international cooperation