Last visit was: 20 Nov 2025, 01:31 It is currently 20 Nov 2025, 01:31
Close
GMAT Club Daily Prep
Thank you for using the timer - this advanced tool can estimate your performance and suggest more practice questions. We have subscribed you to Daily Prep Questions via email.

Customized
for You

we will pick new questions that match your level based on your Timer History

Track
Your Progress

every week, we’ll send you an estimated GMAT score based on your performance

Practice
Pays

we will pick new questions that match your level based on your Timer History
Not interested in getting valuable practice questions and articles delivered to your email? No problem, unsubscribe here.
Close
Request Expert Reply
Confirm Cancel
User avatar
anothermillenial
Joined: 21 Jul 2018
Last visit: 14 Aug 2020
Posts: 151
Own Kudos:
455
 [3]
Given Kudos: 80
Location: United States
Concentration: General Management, Social Entrepreneurship
Posts: 151
Kudos: 455
 [3]
2
Kudos
Add Kudos
1
Bookmarks
Bookmark this Post
User avatar
chrtpmdr
User avatar
Current Student
Joined: 24 Jul 2019
Last visit: 05 Oct 2022
Posts: 202
Own Kudos:
Given Kudos: 161
GMAT 1: 730 Q46 V45
GPA: 3.9
GMAT 1: 730 Q46 V45
Posts: 202
Kudos: 533
Kudos
Add Kudos
Bookmarks
Bookmark this Post
User avatar
jabhatta2
Joined: 15 Dec 2016
Last visit: 21 Apr 2023
Posts: 1,294
Own Kudos:
Given Kudos: 188
Posts: 1,294
Kudos: 317
Kudos
Add Kudos
Bookmarks
Bookmark this Post
User avatar
KarishmaB
Joined: 16 Oct 2010
Last visit: 19 Nov 2025
Posts: 16,267
Own Kudos:
77,001
 [3]
Given Kudos: 482
Location: Pune, India
Expert
Expert reply
Active GMAT Club Expert! Tag them with @ followed by their username for a faster response.
Posts: 16,267
Kudos: 77,001
 [3]
2
Kudos
Add Kudos
1
Bookmarks
Bookmark this Post
joshnsit
Two genes BRCA1 and BRCA2 are linked to hereditary breast cancer. Therefore in order to decrease the annual number of mammogram tests administered across a population and to more accurately assess a woman's individual risk of breast cancer, all women should be tested for these genes.

Which of the following is the assumption?

A. Some women who are tested for the two genes will subsequently undergo mammograms on a less frequent basis than they used to.
B. The majority of breast cancer patients have no family history of the disease.
C. Researchers may have identified a third breast cancer gene that is linked with hereditary breast cancer.
D. Women who have these genes have an 90% chance of getting breast cancer while women who don't have these genes have only a 20% chance of getting breast cancer.
E. The presence of BRCA1 and BRCA 2 can explain upto to 50% of hereditary cases

OA l8r


Observation: Two genes BRCA1 and BRCA2 are linked to hereditary breast cancer.

Plan: All women should be tested for these genes

Aim: Decrease the annual number of mammogram tests administered across a population and to more accurately assess a woman's individual risk of breast cancer

What is an assumption?
An assumption would be something that the plan assumes to be true for the aim to take place.

A. Some women who are tested for the two genes will subsequently undergo mammograms on a less frequent basis than they used to.

Correct. The argument is assuming that there will be a decrease in number of mammograms if women are tested for these genes. Only then can the aim of "decrease the annual number of mammogram tests administered across a population" materialise.

B. The majority of breast cancer patients have no family history of the disease.

This weakens our conclusion. It is not the assumption.

C. Researchers may have identified a third breast cancer gene that is linked with hereditary breast cancer.

Irrelevant.

D. Women who have these genes have an 90% chance of getting breast cancer while women who don't have these genes have only a 20% chance of getting breast cancer.

Certainly something that gives figures such as 90% and 20% cannot be an assumption. 0%, 50% or 100% can still play a role in certain questions but certainly not something like 20% or 90% until and unless these figures are mentioned in the original argument.

jabhatta2 - If the numbers were changed to 100% and 0% respectively, we don't NEED this to be true for our conclusion. We just want to reduce the number of tests. As long as the genes are indicative of probabilities, our argument is fine. We are looking to reduce the number of tests, not abolish them altogether.

E. The presence of BRCA1 and BRCA 2 can explain upto to 50% of hereditary cases.

Again, we don't need them to explain upto 50% of hereditary cases. They could explain only 30% or they could explain 70%. As long as the genes do explain some hereditary cases, our argument is fine.

Answer (A)
User avatar
KeyurJoshi
Joined: 28 Aug 2019
Last visit: 30 Aug 2023
Posts: 147
Own Kudos:
Given Kudos: 405
Location: India
GMAT 1: 710 Q49 V38
GPA: 3.6
WE:Business Development (Computer Software)
Products:
Kudos
Add Kudos
Bookmarks
Bookmark this Post
I'll try to give this question a shot, I narrowed down to A and D but did not find D useful after negating it..

BRCA1 and BRCA2 <----> breast cancer.
All women should be tested for these genes ---> DECREASE the annual number of MT and accurately ASSESS risk of breast cancer,

Goal: REDUCE no. of MT and ASSESS accurately risk of breast cancer
Any choice post-negation, should counter these goals.

Lets negate A,
A. Some women who are tested for the two genes will NOT subsequently undergo mammograms on a less frequent basis than they used to. =
Implies that some women tested for the 2 genes WILL undergo MT on a FREQUENT basis than they used to
This will lead to increase in the MT.
Conclusion doesn't stand. (This may be a little weak bc of usage of "some women" but still the best of all)

D. Women who have these genes have 90% chance of getting breast cancer while women who don't have these genes have only a 20% chance of getting breast cancer.
Negating this choice will not have significant impact on the conclusion for e.g. Women who have these genes DONT HAVE 90% chance of breast cancer then what is their chance of getting cancer ? We simply dont know.
avatar
mk96
Joined: 14 Mar 2018
Last visit: 18 Sep 2022
Posts: 79
Own Kudos:
Given Kudos: 194
Location: India
Concentration: General Management, Finance
Schools: IIMA PGPX'22
GPA: 4
WE:Corporate Finance (Finance: Investment Banking)
Schools: IIMA PGPX'22
Posts: 79
Kudos: 22
Kudos
Add Kudos
Bookmarks
Bookmark this Post
VSabc
Two genes BRCA1 and BRCA2 are linked to hereditary breast cancer. (premise) Therefore in order to decrease the annual number of mammogram tests administered across a population and to more accurately assess a woman's individual risk of breast cancer, all women should be tested for these genes. (conclusion)
We have to pick the answer which lets us conclude from the premise. Conclusion is to reduce woman's risk of breast cancer and we know the two genes are linked to hereditary breast cancer.
A. Seems pretty good, let's keep it for the time being
B. If this was true, checking for the two genes wouldn't help at all. Wrong choice
C. So what? Does it add any value in our question stem? Probably not, rejected
D. Most contentious so far from posts above. Question is asking about an assumption which should be pretty concrete. Can the assumption really be based upon precise nos. It is saying as if 'I'll climb Mount Everest only if it is 8933.2m and I won't if it is 8933.5m" Doesn't seem likely that the conclusion (women should undergo the test) shall be considered only if 90% stat is met. Rejected..
E. Again, too precise % figures. Rejected

Now, let's consider A as an answer choice. Objective is to lower the no. of mammograms and assess the risk more accurately and hence reduce it. If the women are tested for the two genes, they need not undergo the mammogram but still can be diagnosed more accurately. Hence, there will be fewer mammograms for women who have undergone the test for 2 genes. Hence, the answer choice A. Hope this helps.



Hi can someone confirm if my understanding is clear?
If let us say there are 100 womans who are tested for these genes. Out of them let us suppose 50 tested positive for these genes but the other 50 got negatively tested. Then that mean the negatively tested women will not go as frequently as they used to prior ? is that how A is correct? First testing of genes happen and then mammograms, right? These are two different processes? Correct?

bEST,
mK
User avatar
KeyurJoshi
Joined: 28 Aug 2019
Last visit: 30 Aug 2023
Posts: 147
Own Kudos:
153
 [2]
Given Kudos: 405
Location: India
GMAT 1: 710 Q49 V38
GPA: 3.6
WE:Business Development (Computer Software)
Products:
2
Kudos
Add Kudos
Bookmarks
Bookmark this Post
mk96
VSabc
Two genes BRCA1 and BRCA2 are linked to hereditary breast cancer. (premise) Therefore in order to decrease the annual number of mammogram tests administered across a population and to more accurately assess a woman's individual risk of breast cancer, all women should be tested for these genes. (conclusion)
We have to pick the answer which lets us conclude from the premise. Conclusion is to reduce woman's risk of breast cancer and we know the two genes are linked to hereditary breast cancer.
A. Seems pretty good, let's keep it for the time being
B. If this was true, checking for the two genes wouldn't help at all. Wrong choice
C. So what? Does it add any value in our question stem? Probably not, rejected
D. Most contentious so far from posts above. Question is asking about an assumption which should be pretty concrete. Can the assumption really be based upon precise nos. It is saying as if 'I'll climb Mount Everest only if it is 8933.2m and I won't if it is 8933.5m" Doesn't seem likely that the conclusion (women should undergo the test) shall be considered only if 90% stat is met. Rejected..
E. Again, too precise % figures. Rejected

Now, let's consider A as an answer choice. Objective is to lower the no. of mammograms and assess the risk more accurately and hence reduce it. If the women are tested for the two genes, they need not undergo the mammogram but still can be diagnosed more accurately. Hence, there will be fewer mammograms for women who have undergone the test for 2 genes. Hence, the answer choice A. Hope this helps.



Hi can someone confirm if my understanding is clear?
If let us say there are 100 womans who are tested for these genes. Out of them let us suppose 50 tested positive for these genes but the other 50 got negatively tested. Then that mean the negatively tested women will not go as frequently as they used to prior ? is that how A is correct? First testing of genes happen and then mammograms, right? These are two different processes? Correct?

bEST,
mK
mk96
BRCA genes are basically BReast CAncer genes (when mutated, they destroy cells)
So 50 women who've been tested negative for BRCA-1/BRCA-2 genes undergo Mammogram tests LESS FREQUENTLY.

For example,
Each of the 100 women went for mammogram tests 5 times per year
So the total annual no. of mammogram tests = 500 / yr

Now after the gene testing for all 100 women,

Each of the 50 women tested positive for these genes will undergo mammogram test 5 times annually, just like before.
Total no. of mammogram tests for +vely tested women = 250

BUT,
Each of the 50 women tested negative for these genes will undergo mammogram test twice a year (LESS FREQUENT)
Total no. of mammogram tests for -vely tested women = 100

Total no. of mammogram tests for all women = 350 / yr
So by testing genes we have assessed risked accurately and reduced no. of mammogram tests by 150.
User avatar
Rainman91
Joined: 03 Jul 2020
Last visit: 23 Mar 2023
Posts: 87
Own Kudos:
Given Kudos: 120
Posts: 87
Kudos: 33
Kudos
Add Kudos
Bookmarks
Bookmark this Post
khoathanglong
Though A seems to be right, I still doubt it.
Conclusion: to reduce the number of tests -> all women should be tested
in A: some women is tested -> Reduce number of tests
How can sufficient and necessary condition apply in this case?
Some experts please help!

I think I am going through the argument with the same thought process. And this is stemming from the fact that we aren't sure what Mammograms 100% do. Googling it says that it is an X-ray that finds early detection of cancer or other issues. Now, if the women who KNOW that they have the 2 genes, then wouldn't they be testing more often? Or does knowing that a person has these 2 genes means that they will need to take another test other than Mammogram?
User avatar
sanjayparihar16
Joined: 12 Apr 2018
Last visit: 03 Dec 2024
Posts: 158
Own Kudos:
Given Kudos: 426
Posts: 158
Kudos: 145
Kudos
Add Kudos
Bookmarks
Bookmark this Post
KarishmaB
joshnsit
Two genes BRCA1 and BRCA2 are linked to hereditary breast cancer. Therefore in order to decrease the annual number of mammogram tests administered across a population and to more accurately assess a woman's individual risk of breast cancer, all women should be tested for these genes.

Which of the following is the assumption?

A. Some women who are tested for the two genes will subsequently undergo mammograms on a less frequent basis than they used to.
B. The majority of breast cancer patients have no family history of the disease.
C. Researchers may have identified a third breast cancer gene that is linked with hereditary breast cancer.
D. Women who have these genes have an 90% chance of getting breast cancer while women who don't have these genes have only a 20% chance of getting breast cancer.
E. The presence of BRCA1 and BRCA 2 can explain upto to 50% of hereditary cases

OA l8r


Observation: Two genes BRCA1 and BRCA2 are linked to hereditary breast cancer.

Plan: All women should be tested for these genes

Aim: Decrease the annual number of mammogram tests administered across a population and to more accurately assess a woman's individual risk of breast cancer

What is an assumption?
An assumption would be something that the plan assumes to be true for the aim to take place.

A. Some women who are tested for the two genes will subsequently undergo mammograms on a less frequent basis than they used to.

Correct. The argument is assuming that there will be a decrease in number of mammograms if women are tested for these genes. Only then can the aim of "decrease the annual number of mammogram tests administered across a population" materialise.

B. The majority of breast cancer patients have no family history of the disease.

This weakens our conclusion. It is not the assumption.

C. Researchers may have identified a third breast cancer gene that is linked with hereditary breast cancer.

Irrelevant.

D. Women who have these genes have an 90% chance of getting breast cancer while women who don't have these genes have only a 20% chance of getting breast cancer.

Certainly something that gives figures such as 90% and 20% cannot be an assumption. 0%, 50% or 100% can still play a role in certain questions but certainly not something like 20% or 90% until and unless these figures are mentioned in the original argument.

jabhatta2 - If the numbers were changed to 100% and 0% respectively, we don't NEED this to be true for our conclusion. We just want to reduce the number of tests. As long as the genes are indicative of probabilities, our argument is fine. We are looking to reduce the number of tests, not abolish them altogether.

E. The presence of BRCA1 and BRCA 2 can explain upto to 50% of hereditary cases.

Again, we don't need them to explain upto 50% of hereditary cases. They could explain only 30% or they could explain 70%. As long as the genes do explain some hereditary cases, our argument is fine.

Answer (A)


Thank you KarishmaB for the great explanation.

My question is regarding option B. In question stem, it says "Hereditary disease" and option B talks about "family history of disease". Can't we just discard this choice this basis only because we already know that the disease is [hereditary == family history of disease]. So this statement is not adding any new information.
User avatar
Divijakanneganty
Joined: 05 Jun 2020
Last visit: 13 Aug 2024
Posts: 40
Own Kudos:
Given Kudos: 78
Location: India
Concentration: Leadership, Strategy
GMAT 1: 690 Q48 V36
GMAT 2: 640 Q48 V29
GMAT 2: 640 Q48 V29
Posts: 40
Kudos: 5
Kudos
Add Kudos
Bookmarks
Bookmark this Post
Conclusion: To REDUCE the no.of mammograms & to assess risk -> Test has to be done
Which of the following is the assumption?

A. Some women who are tested for the two genes will subsequently undergo mammograms on a less frequent basis than they used to.
These tests reduce the no.of mammograms
B. The majority of breast cancer patients have no family history of the disease.
Weakens the conclusion, as testing all the women for these genes would futile
C. Researchers may have identified a third breast cancer gene that is linked with hereditary breast cancer.
Irrelevant
D. Women who have these genes have an 90% chance of getting breast cancer while women who don't have these genes have only a 20% chance of getting breast cancer.
Even though the risk levels are known, it doesn't reduce the no.of mammograms administered
E. The presence of BRCA1 and BRCA 2 can explain upto to 50% of hereditary cases
Addresses the accuracy part but not the no.of mammograms part


OA l8r[/quote]
User avatar
andrewbrown_user1
Joined: 28 Jul 2023
Last visit: 25 Jun 2024
Posts: 4
Own Kudos:
Given Kudos: 213
Posts: 4
Kudos: 1
Kudos
Add Kudos
Bookmarks
Bookmark this Post
Here is why I think D is wrong:

"Women who have these genes have an 90% chance of getting breast cancer while women who don't have these genes have only a 20% chance of getting breast cancer."

Women who have these genes have a 90% chance of getting breast cancer : ok, this does not mean that these women definitely have cancer. There is a high likelihood that they might be develop cancer in the future. Thus with annual mammogram testing, these women can be track the presence of cancer in their body. Thus, the annual mammogram testing does NOT decrease.

women who don't have these genes have only a 20% chance of getting breast cancer : so women who don't have the aforementioned genes have a 20% chance of developing cancer. Does that mean that these women should not annually perform mammogram testing to track their health? No, there is still a 20% chance these women could develop cancer. So they would still need to perform the mammogram tests. Thus, the annual mammogram testing does NOT decrease.

Therefore Option D is irrelevant
User avatar
VerbalBot
User avatar
Non-Human User
Joined: 01 Oct 2013
Last visit: 04 Jan 2021
Posts: 18,832
Own Kudos:
Posts: 18,832
Kudos: 986
Kudos
Add Kudos
Bookmarks
Bookmark this Post
Hello from the GMAT Club VerbalBot!

Thanks to another GMAT Club member, I have just discovered this valuable topic, yet it had no discussion for over a year. I am now bumping it up - doing my job. I think you may find it valuable (esp those replies with Kudos).

Want to see all other topics I dig out? Follow me (click follow button on profile). You will receive a summary of all topics I bump in your profile area as well as via email.
   1   2 
Moderators:
GMAT Club Verbal Expert
7443 posts
GMAT Club Verbal Expert
231 posts
189 posts