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Mice that have been given morphine are very likely to

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Mice that have been given morphine are very likely to [#permalink]

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Mice that have been given morphine are very likely to develop blood poisoning because bacteria that normally reside in the intestine typically respond to morphine by migrating into the bloodstream. However, when mice are given both morphine and the new drug naltrexone, blood poisoning is much less frequent, although it does still occur. These results provide support for researchers’ prediction that naltrexone will turn out to be toxic to certain types of bacteria.

Which of the following, if discovered to be true, would most seriously weaken the support for the researchers’ prediction?

A. After being administered to mice, naltrexone does not pass from the bloodstream into the intestine.
B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria into the bloodstream.
C. Mice that have been given naltrexone but not morphine have no greater risk of developing blood poisoning than do mice that have not been given either substance.
D. The increased risk of blood poisoning is not the only harmful effect on mice of being given morphine.
E. Conditions other than the presence of intestinal bacteria in the bloodstream can cause blood poisoning in mice.
[Reveal] Spoiler: OA
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 12 Nov 2008, 12:19
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I think its B..

it says the nextrone doesnt kill any bectaria but stops morphine from doing what it previously did..
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 12 Nov 2008, 14:18
A. After being administered to mice, naltrexone does not pass from the bloodstream
into the intestine. [Its bacteria that causes the poison – eliminate it]
B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria
into the bloodstream. [ This should result in less poisoning]
C. Mice that have been given naltrexone but not morphine have no greater risk of
developing blood poisoning than do mice that have not been given either
substance. [Irrelevant]
D. The increased risk of blood poisoning is not the only harmful effect on mice of
being given morphine.[Effects is out of argument]
E. Conditions other than the presence of intestinal bacteria in the bloodstream can
cause blood poisoning in mice. [Hold]


Answer: E
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 12 Nov 2008, 15:29
hanumayamma wrote:
B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria
into the bloodstream. [ This should result in less poisoning]
E. Conditions other than the presence of intestinal bacteria in the bloodstream can cause blood poisoning in mice. [Hold]

Answer: E


The conclusion from the statement is that: "results provide support for researchers’ prediction that naltrexone will turn out to be toxic
to certain types of bacteria."


We are looking for a statement that breaks the logic between naltrexone and bacteria.

B. does this by saying that naltrexone acts on the morphine, not the Bacteria.
E. This MAY be true but it does not weaken the conclusion.

OA???
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 12 Nov 2008, 19:59
This is a tough one.
B for me. Whats the OA, botirvoy?
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 13 Nov 2008, 01:46
C.
the conclusion is about nextrolene being toxic to bacteria ...
(C)suggests that nextrolene will have no effect whatsoever on mice, so it weakens the argument that nextrolene can be toxic to certain types of bacteria...
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 13 Nov 2008, 09:44
answer B.the statement says that naxto.... prevents morphene from migrating bacteria into the blood stream thus nullifying the presence of the bacteria in the blood stream altogether.so morphene does not kill bacteria.
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 13 Nov 2008, 17:35
botirvoy wrote:
Mice that have been given morphine are very likely to develop blood poisoning because
bacteria that normally reside in the intestine typically respond to morphine by migrating
into the bloodstream. However, when mice are given both morphine and the new drug
naltrexone, blood poisoning is much less frequent, although it does still occur. These
results provide support for researchers’ prediction that naltrexone will turn out to be toxic
to certain types of bacteria.
Which of the following, if discovered to be true, would most seriously weaken the
support for the researchers’ prediction?
A. After being administered to mice, naltrexone does not pass from the bloodstream
into the intestine.
B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria
into the bloodstream.
C. Mice that have been given naltrexone but not morphine have no greater risk of
developing blood poisoning than do mice that have not been given either
substance.
D. The increased risk of blood poisoning is not the only harmful effect on mice of
being given morphine.
E. Conditions other than the presence of intestinal bacteria in the bloodstream can
cause blood poisoning in mice.



has to be B.

bacteria that normally reside in the intestine typically respond to morphine by migrating
into the bloodstream and cause blood poisoning. C is that N will be toxic to certain bacteria

Weaken

Look for choice that says N will NOT be toxic to intestinal bacteria. If N were to suppress the B-M interaction, blood poisoning would not occur and it cannot turn out to be toxic.

E says that some thing else causes BP. the conclusion here is more weakened by B by saying that N will not turn out to be toxic afterall.
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 08 Jun 2015, 20:07
Can anybody explain why C is not a better answer than B.
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 08 Jun 2015, 23:56
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282552 wrote:
Can anybody explain why C is not a better answer than B.



Morphine leads to blood poisoning in Mice because it makes bacteria migrate from intestine into the bloodstream.
Morphine with naltrexone leads to blood poisoning much less frequently.

Conclusion:
Naltrexone is will kill some types of bacteria.

We need to weaken it. There are tons of things which will weaken, There can be a dozen different explanations for why morphine with naltrexone doesn't cause blood poisoning. Perhaps, naltrexone reacts with morphine and neutralises the compound in it which causes the bacteria to migrate.
Naltrexone doesn't kill the bacteria but makes it ineffective such that they don to cause poisoning.
or Naltrexone affects the intestine in such a way that bacteria cannot migrate out of it.
or many other different explanations.


B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria
into the bloodstream.

Makes perfect sense.

C. Mice that have been given naltrexone but not morphine have no greater risk of
developing blood poisoning than do mice that have not been given either
substance.

So this says that naltrexone does not cause blood poisoning i.e. it doesn't make bacteria migrate form intestine to bloodstream. It does not weaken that it kills some bacteria.
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Re: Mice that have been given morphine are very likely to [#permalink]

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Mice that have been given morphine are very likely to develop blood poisoning because
bacteria that normally reside in the intestine typically respond to morphine by migrating
into the bloodstream. However, when mice are given both morphine and the new drug
naltrexone, blood poisoning is much less frequent, although it does still occur. These
results provide support for researchers’ prediction that naltrexone will turn out to be toxic
to certain types of bacteria.

Which of the following, if discovered to be true, would most seriously weaken the
support for the researchers’ prediction?

The prediction is that naltrexone is toxic to bacteria since mice given morphine with naltrexone don't develop blood poisoning, normally caused by the intestine's response to morphine. To weaken this prediction one needs to find a different mechanism for naltrexone.
A. After being administered to mice, naltrexone does not pass from the bloodstream
into the intestine. Where naltrexone passes isn't relevant.
B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria
into the bloodstream.

C. Mice that have been given naltrexone but not morphine have no greater risk of
developing blood poisoning than do mice that have not been given either
substance. We already know that morphine induces blood poisoning. What occurs in the absence of morphine isn't relevant.
D. The increased risk of blood poisoning is not the only harmful effect on mice of
being given morphine. Anything other than blood poisoning is out of scope
E. Conditions other than the presence of intestinal bacteria in the bloodstream can
cause blood poisoning in mice. Other causes of blood poisoning are out of scope.
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Re: Mice that have been given morphine are very likely to [#permalink]

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p1 :- bacteria + morphine ==> blood cancer
P2 :- morphine + Naltrexone + Bacteria ==> less frequency of blood cancer
conclusion :- Naltrexone toxic for some bacteria

what if Naltrexone has no effect on Bacteria rather effect on morphine
B is the answer
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Re: Mice that have been given morphine are very likely to [#permalink]

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Mice that have been given morphine are very likely to develop blood poisoning because bacteria that normally reside in the intestine typically respond to morphine by migrating into the bloodstream. However, when mice are given both morphine and the new drug naltrexone, blood poisoning is much less frequent, although it does still occur. These results provide support for researchers’ prediction that naltrexone will turn out to be toxic to certain types of bacteria.

Which of the following, if discovered to be true, would most seriously weaken the support for the researchers’ prediction?

A. After being administered to mice, naltrexone does not pass from the bloodstream into the intestine.
That means morphine released the bacteria into blood stream and the N acted on that bacteria .
Strengthen

B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria into the bloodstream.
N acts on M, not the bacteria .
Weakens

C. Mice that have been given naltrexone but not morphine have no greater risk of developing blood poisoning than do mice that have not been given either substance.
Talks about blood poisioning rather than N action on bacteria.
Irrilevent
D. The increased risk of blood poisoning is not the only harmful effect on mice of being given morphine. Talks about harmful effects of blood poisoning.
Irrilevent

E. Conditions other than the presence of intestinal bacteria in the bloodstream can cause blood poisoning in mice. Oos / opposite answer

Talks about conditions other than bacteria itself . That means it doesn't matter whether N acts on bacteria , blood poisoning occurs from other means .



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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 10 Jul 2016, 22:46
B it is.

had 2 contenders A and B

find A is irrelevant as it does not satisfy toxicity anywhere.

B however says that the second drug inhibits and not kill the bacteria, which surely weakens the claim
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 07 Apr 2017, 09:45
seofah wrote:
Mice that have been given morphine are very likely to develop blood poisoning because bacteria that normally reside in the intestine typically respond to morphine by migrating into the bloodstream. However, when mice are given both morphine and the new drug naltrexone, blood poisoning is much less frequent, although it does still occur. These results provide support for researchers’ prediction that naltrexone will turn out to be toxic to certain types of bacteria.

Which of the following, if discovered to be true, would most seriously weaken the support for the researchers’ prediction?

A. After being administered to mice, naltrexone does not pass from the bloodstream into the intestine.
B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria into the bloodstream.
C. Mice that have been given naltrexone but not morphine have no greater risk of developing blood poisoning than do mice that have not been given either substance.
D. The increased risk of blood poisoning is not the only harmful effect on mice of being given morphine.
E. Conditions other than the presence of intestinal bacteria in the bloodstream can cause blood poisoning in mice.


without a doubt it's B.
B says that new drug "destroys" morphine...definitely a weakener!
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Mice that have been given morphine are very likely to [#permalink]

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New post 15 Aug 2017, 03:37
I go for 'C'

B is actually strengthening the argument, Naltrexone inhibits action of bacteria in response to morphine but still poisoning is occurring which indicates that naltrexone might be toxic to certain type of bacteria .

Can anyone pl help here?
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 21 Aug 2017, 22:42
Explanation:

The argument states that naltrexone is harmful for many strains of bacteria. The evidence to support this conclusion is that when mice were given this new drug along with morphine, they had fewer cases of blood poisoning than they did in situations where the mice were given only morphine, which triggered harmful intestinal bacteria to mix with the blood of the mice. We need to prove that despite the reduction in the incidences of blood poisoning after the administration of the drug, the new drug has not damaging effect on the harmful bacteria.

Whether the new drug moves or not is irrelevant in knowing its effect on the bacteria.
CORRECT. As per this option, the new drug does not kill harmful bacteria. Rather, it only hampers the movement of these bacteria to the blood of the mice. Thus, whereas this new drug can be said to be good for the mice, since it prevents the cases of blood poisoning, it does not have a direct damaging effect on the harmful bacteria itself. This helps weaken the conclusion.
Mice which are given only the new drugs have the same chances of being bold poisoned. This will only prove the negative effect of the new drug on the mice. But this still does not clarify the relation between the new drug and the harmful bacteria.
We are not probing into the number of harmful effects of morphine.
‘Other causes of blood poisoning’ is again out of scope.
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Mice that have been given morphine are very likely to [#permalink]

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New post 05 Dec 2017, 04:14
I'm sorry but I don't get B. I think my confusion stems from the use of 'inhibit'

"Naltrexone inhibits morphine from triggering the migration of intestinal bacteria into the bloodstream."

If Naltrexone inhibits morphine from triggering the migration of bacteria into the bloodstream, wouldn't that mean it completely prevents bacteria from getting through? (inhibit usually means completely stops/prevents).

Yet in the passage, it says the combination of the two drugs reduces poisoning, but doesn't completely stop it.

"However, when mice are given both morphine and the new drug naltrexone, blood poisoning is much less frequent, although it does still occur."

So blood poisoning does still occur.

If naltrexone inhibits bacteria from getting into the system, what accounts for the cases where blood poisoning still occurs?

A might be the best answer of the lot, but this still stuck out as a glaring flaw for me and on the exam i'd be very uncomfortable confirming it as an answer. Anyone care to elaborate?
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Re: Mice that have been given morphine are very likely to [#permalink]

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New post 05 Dec 2017, 04:42
In addition to "stop", apparently "inhibit" can also mean "hinder/resist".

So, that resistance/hindrance might not ultimately result in 100% success (in preventing migration of intestinal bacteria into the bloodstream).
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Mice that have been given morphine are very likely to [#permalink]

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[quote="seofah"]Mice that have been given morphine are very likely to develop blood poisoning because bacteria that normally reside in the intestine typically respond to morphine by migrating into the bloodstream. However, when mice are given both morphine and the new drug naltrexone, blood poisoning is much less frequent, although it does still occur. These results provide support for researchers’ prediction that naltrexone will turn out to be toxic to certain types of bacteria.

Which of the following, if discovered to be true, would most seriously weaken the support for the researchers’ prediction?

A. After being administered to mice, naltrexone does not pass from the bloodstream into the intestine.
B. Naltrexone inhibits morphine from triggering the migration of intestinal bacteria into the bloodstream.
C. Mice that have been given naltrexone but not morphine have no greater risk of developing blood poisoning than do mice that have not been given either substance.
D. The increased risk of blood poisoning is not the only harmful effect on mice of being given morphine.
E. Conditions other than the presence of intestinal bacteria in the bloodstream can cause blood poisoning in mice.



A. Incorrect. It is irrelevant to know the passage process of Naltrexone. It can still turnout to be toxic to certain type of bacteria
B. Correct. If this is true, then Nal. is not actually toxic to bacteria but inhibiting Mor. to make the reaction
C. Incorrect. Magnitude of the risk is irrelevant here. This simply doesn't help us evaluate whether Nal. is toxic to bacteria or not.
D. Incorrect. We don't care about other effects of Mor.
E. Incorrect. Again, we cannot infer from his whether Nal. is toxic to Bacteria or not.

Hope this helps!
Mice that have been given morphine are very likely to   [#permalink] 05 Dec 2017, 06:51

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