Because of differences in the humans body's internal pressure and the ocean's, it is essential that a diver returning to the surface ascends slowly or they will suffer a painful condition known as the "bends."
A. differences in the human body's internal pressure and the ocean's, it is essential that a diver returning to the surface ascends slowly or they
B. the difference between the human body's internal pressure and the ocean's, it is essential that a diver returning to the surface ascend slowly or they
C. the difference in the human body's internal pressure and that of the ocean, it is essential that a diver returning to the surface ascends slowly or he
D. differences in the human body's internal pressure and that of the ocean, it is essential that a diver returning to the surface ascend slowly or they
E. the difference between the internal pressure of the human body and that of the ocean, it is essential that a diver returning to the surface ascend slowly or he
in this, the issue is "idioms".
"difference" accompany with "between" and "between" goes along with "and".
considering this, B & E left.
Between B and E, B has a subject should be singular instead of "they".
Hence, the answer is E.