(A) and with its superiority to chloroform being
Option (A) is wordy and redundant. The phrase "with its superiority to chloroform being" adds unnecessary verbiage to the sentence without adding any essential information.
Option (B) is the most appropriate choice in this context. It provides a concise and grammatically correct way of connecting the two clauses in the sentence. The phrase "and its superiority to chloroform" effectively conveys the intended meaning without unnecessary complexity.
Correct Choice(C) and its superiority over chloroform had been
Option (C) creates an awkward tense mismatch in the sentence. The use of "had been" is unnecessary and doesn't fit well with the rest of the sentence.
(D) its superiority over chloroform
Option (D) is concise and grammatically correct, but it lacks the conjunction "and," which is needed to connect the two clauses and show the relationship between the demonstrated physiological effects of diethyl ether and its superiority to chloroform.
(E) with its superiority to chloroform having been
Option (E) introduces the participle phrase "having been," which makes the sentence unnecessarily complex. It also disrupts the smooth flow of the sentence and doesn't fit well in the context of the sentence.