Bunuel
Once the physiological effects and anesthetic qualities of diethyl ether were demonstrated
and with its superiority to chloroform being proved by William Morton, the medical community rapidly adopted it as the anesthetic of choice.
(A) and with its superiority to chloroform being
(B) and its superiority to chloroform
(C) and its superiority over chloroform had been
(D) its superiority over chloroform
(E) with its superiority to chloroform having been
We are talking about two pasts here, So, had is a need for the earlier past event. The only answer with had is option C.
Anyway, here are details for each option elimination:
(A) and
with its superiority
to chloroform being - Not parallel
(B) and its superiority
to chloroform - Not parallel,
(C) and its superiority over chloroform had been - Correct
(D)
its superiority over chloroform - No and here
(E)
with its superiority
to chloroform having been - Over is giving more precise meaning than to. Also and is needed.
C